Matches in SemOpenAlex for { <https://semopenalex.org/work/W2279056276> ?p ?o ?g. }
- W2279056276 abstract "There is relatively little known about the fate of human pharmaceuticals once they are released into the aquatic environment and what adverse impacts these compounds have on exposed aquatic organisms. Both of these factors are essential in defining the potential risk pharmaceuticals pose in the aquatic environment. For this project up to 14 human therapeutic agents were selected as representative compounds to assess both their fate and effects within model aquatic systems. Considering sediments often serve as a repository for aquatic contaminants, the interaction of the selected pharmaceuticals with sediment was assessed. The sorption of the selected pharmaceuticals was found to be highly variable. Furthermore, the solution pH and ionic strength, due to Ca, were found to exert a large degree of influence on the extent of sorption observed. These solution parameters, among others, may therefore make it difficult to predict the fate of pharmaceuticals, in terms of their association with sediments, using standardised assessment methods alone. There is an extensive pool of knowledge on pharmaceuticals, in terms of their pharmacological profile, so their distribution within the human body (using the volume of distribution or VD) was compared with their distribution within a sediment / water system (using the partition coefficient or Kd). The correlation between the VD and Kd indicated this relationship provided a reasonable basis for estimating the distribution of drugs within the test sediment / water systems. This finding suggests that further exploration of the use of pharmacological data in understanding the potential fate of pharmaceuticals in aquatic systems is warranted." @default.
- W2279056276 created "2016-06-24" @default.
- W2279056276 creator A5064084636 @default.
- W2279056276 date "2007-01-01" @default.
- W2279056276 modified "2023-09-27" @default.
- W2279056276 title "The Fate and Effects of Human Pharmaceuticals in the Aquatic Environment" @default.
- W2279056276 cites W1599334980 @default.
- W2279056276 cites W1608086260 @default.
- W2279056276 cites W1611872100 @default.
- W2279056276 cites W1775749144 @default.
- W2279056276 cites W1957404983 @default.
- W2279056276 cites W1963712136 @default.
- W2279056276 cites W1963841973 @default.
- W2279056276 cites W1965922002 @default.
- W2279056276 cites W1966206163 @default.
- W2279056276 cites W1969218162 @default.
- W2279056276 cites W1969506987 @default.
- W2279056276 cites W1976683768 @default.
- W2279056276 cites W1977054388 @default.
- W2279056276 cites W1978215948 @default.
- W2279056276 cites W1979999747 @default.
- W2279056276 cites W1980686360 @default.
- W2279056276 cites W1981353259 @default.
- W2279056276 cites W1981775193 @default.
- W2279056276 cites W1981854185 @default.
- W2279056276 cites W1982791644 @default.
- W2279056276 cites W1982950728 @default.
- W2279056276 cites W1983552844 @default.
- W2279056276 cites W1984298514 @default.
- W2279056276 cites W1984750810 @default.
- W2279056276 cites W1987073252 @default.
- W2279056276 cites W1988286516 @default.
- W2279056276 cites W1989493735 @default.
- W2279056276 cites W1990682871 @default.
- W2279056276 cites W1991608935 @default.
- W2279056276 cites W1993926520 @default.
- W2279056276 cites W1994019507 @default.
- W2279056276 cites W1994221839 @default.
- W2279056276 cites W1994936932 @default.
- W2279056276 cites W1999296233 @default.
- W2279056276 cites W2001434046 @default.
- W2279056276 cites W2002481914 @default.
- W2279056276 cites W2003352719 @default.
- W2279056276 cites W2007517456 @default.
- W2279056276 cites W2008733004 @default.
- W2279056276 cites W2009148829 @default.
- W2279056276 cites W2010314650 @default.
- W2279056276 cites W2010806972 @default.
- W2279056276 cites W2012124164 @default.
- W2279056276 cites W2012426530 @default.
- W2279056276 cites W2014866342 @default.
- W2279056276 cites W2015755198 @default.
- W2279056276 cites W2016750121 @default.
- W2279056276 cites W2019698362 @default.
- W2279056276 cites W2020640579 @default.
- W2279056276 cites W2022957234 @default.
- W2279056276 cites W2027127607 @default.
- W2279056276 cites W2027307565 @default.
- W2279056276 cites W2029960321 @default.
- W2279056276 cites W2030011929 @default.
- W2279056276 cites W2032838523 @default.
- W2279056276 cites W2034297284 @default.
- W2279056276 cites W2035007027 @default.
- W2279056276 cites W2035689300 @default.
- W2279056276 cites W2036193141 @default.
- W2279056276 cites W2036949163 @default.
- W2279056276 cites W2037602347 @default.
- W2279056276 cites W2037766564 @default.
- W2279056276 cites W2038176771 @default.
- W2279056276 cites W2038242977 @default.
- W2279056276 cites W2040672128 @default.
- W2279056276 cites W2041283704 @default.
- W2279056276 cites W2041679850 @default.
- W2279056276 cites W2042435517 @default.
- W2279056276 cites W2044116983 @default.
- W2279056276 cites W2045263397 @default.
- W2279056276 cites W2046190423 @default.
- W2279056276 cites W2046871139 @default.
- W2279056276 cites W2048122753 @default.
- W2279056276 cites W2048237300 @default.
- W2279056276 cites W2048664523 @default.
- W2279056276 cites W2049068631 @default.
- W2279056276 cites W2049872392 @default.
- W2279056276 cites W2051029932 @default.
- W2279056276 cites W2052542118 @default.
- W2279056276 cites W2053322034 @default.
- W2279056276 cites W2054458587 @default.
- W2279056276 cites W2059265071 @default.
- W2279056276 cites W2060673571 @default.
- W2279056276 cites W2061950383 @default.
- W2279056276 cites W2063265538 @default.
- W2279056276 cites W2064281959 @default.
- W2279056276 cites W2066329734 @default.
- W2279056276 cites W2069464515 @default.
- W2279056276 cites W2069563927 @default.
- W2279056276 cites W2069841698 @default.
- W2279056276 cites W2070450736 @default.
- W2279056276 cites W2071536080 @default.
- W2279056276 cites W2071594787 @default.
- W2279056276 cites W2073559320 @default.