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• W2279208117 endingPage "13" @default.
• W2279208117 startingPage "13" @default.
• W2279208117 abstract "Dendritic cells (DCs) are considered to play major roles during the induction of T cell immune responses as well as the maintenance of T cell tolerance. Naive CD4(+) T cells have been shown to respond with high plasticity to signals inducing their polarization into effector/helper or regulatory T cells. Data obtained from in vitro generated bone-marrow (BM)-derived DCs as well as genetic mouse models revealed an important but not exclusive role of DCs in shaping CD4(+) T cell responses. Besides the specialization of some conventional DC subsets for the induction of polarized immunity, also the maturation stage, activation of specialized transcription factors and the cytokine production of DCs have major impact on CD4(+) T cells. Since in vitro generated BM-DCs show a high diversity to shape CD4(+) T cells and their high similarity to monocyte-derived DCs in vivo, this review reports data mainly on BM-DCs in this process and only touches the roles of transcription factors or of DC subsets, which have been discussed elsewhere. Here, recent findings on 1) the conversion of naive into anergic and further into Foxp3(-) regulatory T cells (Treg) by immature DCs, 2) the role of RelB in steady state migratory DCs (ssmDCs) for conversion of naive T cells into Foxp3(+) Treg, 3) the DC maturation signature for polarized Th2 cell induction and 4) the DC source of IL-12 for Th1 induction are discussed." @default.
• W2279208117 created "2016-06-24" @default.
• W2279208117 creator A5010988346 @default.
• W2279208117 date "2016-01-01" @default.
• W2279208117 modified "2023-10-18" @default.
• W2279208117 title "Induction of CD4⁺Regulatory and Polarized Effector/helper T Cells by Dendritic Cells" @default.
• W2279208117 cites W1488377901 @default.
• W2279208117 cites W1497241398 @default.
• W2279208117 cites W1503658549 @default.
• W2279208117 cites W1522802573 @default.
• W2279208117 cites W1526621387 @default.
• W2279208117 cites W1532147512 @default.
• W2279208117 cites W1532335239 @default.
• W2279208117 cites W1533618934 @default.
• W2279208117 cites W1542616270 @default.
• W2279208117 cites W1568945049 @default.
• W2279208117 cites W1578357700 @default.
• W2279208117 cites W1583246305 @default.
• W2279208117 cites W1584260869 @default.
• W2279208117 cites W1584463243 @default.
• W2279208117 cites W1606532415 @default.
• W2279208117 cites W1614566767 @default.
• W2279208117 cites W1627771650 @default.
• W2279208117 cites W1767177522 @default.
• W2279208117 cites W1793898094 @default.
• W2279208117 cites W1908361432 @default.
• W2279208117 cites W1922016811 @default.
• W2279208117 cites W1924286396 @default.
• W2279208117 cites W1939484655 @default.
• W2279208117 cites W1945018809 @default.
• W2279208117 cites W1970180138 @default.
• W2279208117 cites W1974381902 @default.
• W2279208117 cites W1975660715 @default.
• W2279208117 cites W1976261525 @default.
• W2279208117 cites W1976750616 @default.
• W2279208117 cites W1976945431 @default.
• W2279208117 cites W1978971257 @default.
• W2279208117 cites W1981802408 @default.
• W2279208117 cites W1984378291 @default.
• W2279208117 cites W1987917362 @default.
• W2279208117 cites W1988170203 @default.
• W2279208117 cites W1991536229 @default.
• W2279208117 cites W1995313125 @default.
• W2279208117 cites W1997708871 @default.
• W2279208117 cites W1998993174 @default.
• W2279208117 cites W1998998882 @default.
• W2279208117 cites W1999280313 @default.
• W2279208117 cites W2000022199 @default.
• W2279208117 cites W2000633690 @default.
• W2279208117 cites W2007070916 @default.
• W2279208117 cites W2009219530 @default.
• W2279208117 cites W2013926690 @default.
• W2279208117 cites W2015823023 @default.
• W2279208117 cites W2016055373 @default.
• W2279208117 cites W2017104717 @default.
• W2279208117 cites W2019815618 @default.
• W2279208117 cites W2020522891 @default.
• W2279208117 cites W2021377837 @default.
• W2279208117 cites W2022088528 @default.
• W2279208117 cites W2028446411 @default.
• W2279208117 cites W2029208213 @default.
• W2279208117 cites W2029771914 @default.
• W2279208117 cites W2030269101 @default.
• W2279208117 cites W2032917521 @default.
• W2279208117 cites W2033172475 @default.
• W2279208117 cites W2035960239 @default.
• W2279208117 cites W2036217777 @default.
• W2279208117 cites W2037916051 @default.
• W2279208117 cites W2038600671 @default.
• W2279208117 cites W2039096179 @default.
• W2279208117 cites W2043283739 @default.
• W2279208117 cites W2045693610 @default.
• W2279208117 cites W2049029166 @default.
• W2279208117 cites W2049946738 @default.
• W2279208117 cites W2050783012 @default.
• W2279208117 cites W2051071985 @default.
• W2279208117 cites W2052086040 @default.
• W2279208117 cites W2052997401 @default.
• W2279208117 cites W2056927031 @default.
• W2279208117 cites W2060735279 @default.
• W2279208117 cites W2064625208 @default.
• W2279208117 cites W2066172186 @default.
• W2279208117 cites W2067600414 @default.
• W2279208117 cites W2067948957 @default.
• W2279208117 cites W2068290887 @default.
• W2279208117 cites W2068639447 @default.
• W2279208117 cites W2068681515 @default.
• W2279208117 cites W2069929656 @default.
• W2279208117 cites W2075582594 @default.
• W2279208117 cites W2077924498 @default.
• W2279208117 cites W2083872083 @default.
• W2279208117 cites W2084006363 @default.
• W2279208117 cites W2085539455 @default.
• W2279208117 cites W2089914460 @default.
• W2279208117 cites W2091916930 @default.
• W2279208117 cites W2092235636 @default.
• W2279208117 cites W2095881540 @default.
• W2279208117 cites W2097298372 @default.

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