Matches in SemOpenAlex for { <https://semopenalex.org/work/W2279225275> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2279225275 endingPage "207" @default.
- W2279225275 startingPage "196" @default.
- W2279225275 abstract "The AA. refer about the assessment of a charcoal-dextran method for the determination of oestrogens receptors in human breast cancer. Corrections for low affinity binding components are performed measuring bound 3H-17 beta estradiol in the absence and presence of non-radioactive 17 beta estradiol or diethylstilbestrol; the method has been previously studied on samples from pregnant rabbit uterus and then applied on human mammary tumors. Results achieved with the routine-utilisation of the present method are reported.It is well known that successful endocrinal treatment of cancer depends on the presence of specific hormone receptors in the cancerous cells. According to the most recent studies it appears that positive treatment would be possible in 6% of cases when there are no receptors, in 46% of cases with average concentration of receptors, and in 81% of cases with concentrations higher than 100 femtomoles/mg of proteins. This study reports on a new method of determination of estrogen receptors utilized in 57 cases of breast cancer. This new charcoal-dextran method, which has been previously tested on samples of pregnant rabbit uteri, measures bond H-17 beta estradiol in the absence and in the presence of nonradioactive 17 beta estradiol or diethylstilbestrol to determine corrections for low affinity binding components. This method appears to be rather precise; it is still possible, however, to overestimate or underrestimate the concentration of estrogen receptors. Routine application of this method is not easy, and needs to be perfected." @default.
- W2279225275 created "2016-06-24" @default.
- W2279225275 creator A5015000795 @default.
- W2279225275 creator A5029370216 @default.
- W2279225275 date "1979-06-01" @default.
- W2279225275 modified "2023-09-23" @default.
- W2279225275 title "[Oestrogen receptors determination in human breast cancer (author's transl)]." @default.
- W2279225275 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/554158" @default.
- W2279225275 hasPublicationYear "1979" @default.
- W2279225275 type Work @default.
- W2279225275 sameAs 2279225275 @default.
- W2279225275 citedByCount "0" @default.
- W2279225275 crossrefType "journal-article" @default.
- W2279225275 hasAuthorship W2279225275A5015000795 @default.
- W2279225275 hasAuthorship W2279225275A5029370216 @default.
- W2279225275 hasConcept C121608353 @default.
- W2279225275 hasConcept C126322002 @default.
- W2279225275 hasConcept C134018914 @default.
- W2279225275 hasConcept C170493617 @default.
- W2279225275 hasConcept C185592680 @default.
- W2279225275 hasConcept C23589133 @default.
- W2279225275 hasConcept C2777164284 @default.
- W2279225275 hasConcept C2781397067 @default.
- W2279225275 hasConcept C2994423619 @default.
- W2279225275 hasConcept C530470458 @default.
- W2279225275 hasConcept C71315377 @default.
- W2279225275 hasConcept C71924100 @default.
- W2279225275 hasConcept C84606932 @default.
- W2279225275 hasConceptScore W2279225275C121608353 @default.
- W2279225275 hasConceptScore W2279225275C126322002 @default.
- W2279225275 hasConceptScore W2279225275C134018914 @default.
- W2279225275 hasConceptScore W2279225275C170493617 @default.
- W2279225275 hasConceptScore W2279225275C185592680 @default.
- W2279225275 hasConceptScore W2279225275C23589133 @default.
- W2279225275 hasConceptScore W2279225275C2777164284 @default.
- W2279225275 hasConceptScore W2279225275C2781397067 @default.
- W2279225275 hasConceptScore W2279225275C2994423619 @default.
- W2279225275 hasConceptScore W2279225275C530470458 @default.
- W2279225275 hasConceptScore W2279225275C71315377 @default.
- W2279225275 hasConceptScore W2279225275C71924100 @default.
- W2279225275 hasConceptScore W2279225275C84606932 @default.
- W2279225275 hasIssue "2" @default.
- W2279225275 hasLocation W22792252751 @default.
- W2279225275 hasOpenAccess W2279225275 @default.
- W2279225275 hasPrimaryLocation W22792252751 @default.
- W2279225275 hasRelatedWork W1978602167 @default.
- W2279225275 hasRelatedWork W2021065129 @default.
- W2279225275 hasRelatedWork W2030251858 @default.
- W2279225275 hasRelatedWork W2045166305 @default.
- W2279225275 hasRelatedWork W2067634959 @default.
- W2279225275 hasRelatedWork W2068408721 @default.
- W2279225275 hasRelatedWork W2090461312 @default.
- W2279225275 hasRelatedWork W2101821182 @default.
- W2279225275 hasRelatedWork W2418691788 @default.
- W2279225275 hasRelatedWork W3032467824 @default.
- W2279225275 hasVolume "15" @default.
- W2279225275 isParatext "false" @default.
- W2279225275 isRetracted "false" @default.
- W2279225275 magId "2279225275" @default.
- W2279225275 workType "article" @default.