FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2279265429> ?p ?o ?g. }

• W2279265429 endingPage "1020" @default.
• W2279265429 startingPage "1019" @default.
• W2279265429 abstract "An 80-year-old woman presented to the internal medicine department for three episodes of melena for 2 days. She reported taking NSAIDs (ibuprofen 1600 mg daily) the prior week. The physical examination was unremarkable with stable vital signs. Laboratory tests were significant for an iron deficiency anemia with hemoglobin ranging from 9.0 to 11.0 g/dL (reference range 12.5–14.5 g/dL). Her past medical history included osteoarthritis (occasional taking of NSAIDs) and hysterectomy. Esophagogastroduodenoscopy showed a black-appearing esophageal mucosa circumferentially occupying the entire body of the second half of the esophagus (Fig. 1). Biopsies of the lesion demonstrated epithelial cell necrosis, with nonspecific inflammatory exudates. The patient gradually recovered after conservative treatments (hydration, intravenous, proton pump inhibitor, sucralfate and total parenteral nutrition). Follow-up upper gastrointestinal endoscopy revealed a remarkable healing of the esophageal wall with no complications (Fig. 2). ‘Black esophagus’ or acute esophageal necrosis (AEN) was first described by Goldenberg et al. in the early 1990s [1, 2]. The incidence of black esophagus is very low, ranging from 0.012 to 0.2 %, and according to the literature, 90 cases have been reported so far [3, 4]. The etiology is unknown in most cases. Most investigators have suggested an ischemic origin. Risk factors include advanced age, male gender, cardiovascular disease, alcoholic ingestion and malnutrition, acute gastric outlet obstruction with gastro-esophageal reflux, diabetes, acute renal failure and trauma. Candidiasis is a rare cause of AEN. An incidental finding in upper endoscopy has also been mentioned [5]. The esophagus has a black-appearing color, with easily crumbled mucosa predominantly affecting the lower two-thirds of the esophagus. Esophageal transit with barium swallow shows if there is any potential of an esophageal motility disorders, and computed tomography (CT scan) may reveal a thickened distal esophagus, a hiatal hernia, and a distended fluid-filled stomach with possible gastric outlet obstruction. Endoscopic biopsies show epithelial necrosis, with non-specific inflammatory exudates, and ulcerations. Esophageal bleeding (melena and hematemesis) is the most common presentation. The differential diagnosis of black esophagus includes: the ingestion of corrosive agents, infections, esophageal melanosis and pseudomelanosis, acanthosis nigricans and coal-dust miner. The main reported complications of AEN are stenosis and strictures. Regarding the therapeutic approach, most authors recommend adequate hydration, the use of a proton pump inhibitor, sucralfate, and treating the esophageal infection, if present. Additionally, treating the patient’s comorbidities such as restoration of the iron adequacy, and elimination of any esophageal infection as well as abstinence from alcohol, which may have been an aggravating factor. The prognosis is usually hopeful if other comorbidities do not influence the outcome. & Michalis Galanopoulos galanopoulosdr@gmail.com" @default.
• W2279265429 created "2016-06-24" @default.
• W2279265429 creator A5028285577 @default.
• W2279265429 creator A5035088676 @default.
• W2279265429 creator A5042731625 @default.
• W2279265429 creator A5075318002 @default.
• W2279265429 date "2015-11-24" @default.
• W2279265429 modified "2023-09-27" @default.
• W2279265429 title "Black esophagus: an uncommon cause of upper gastrointestinal bleeding" @default.
• W2279265429 cites W2008143715 @default.
• W2279265429 cites W2030714088 @default.
• W2279265429 cites W2032195421 @default.
• W2279265429 cites W2071490855 @default.
• W2279265429 cites W2088588232 @default.
• W2279265429 doi "https://doi.org/10.1007/s11739-015-1360-z" @default.
• W2279265429 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26602388" @default.
• W2279265429 hasPublicationYear "2015" @default.
• W2279265429 type Work @default.
• W2279265429 sameAs 2279265429 @default.
• W2279265429 citedByCount "1" @default.
• W2279265429 countsByYear W22792654292020 @default.
• W2279265429 crossrefType "journal-article" @default.
• W2279265429 hasAuthorship W2279265429A5028285577 @default.
• W2279265429 hasAuthorship W2279265429A5035088676 @default.
• W2279265429 hasAuthorship W2279265429A5042731625 @default.
• W2279265429 hasAuthorship W2279265429A5075318002 @default.
• W2279265429 hasBestOaLocation W22792654291 @default.
• W2279265429 hasConcept C126322002 @default.
• W2279265429 hasConcept C126838900 @default.
• W2279265429 hasConcept C2776345487 @default.
• W2279265429 hasConcept C2777819096 @default.
• W2279265429 hasConcept C2778451229 @default.
• W2279265429 hasConcept C61434518 @default.
• W2279265429 hasConcept C71924100 @default.
• W2279265429 hasConcept C90924648 @default.
• W2279265429 hasConceptScore W2279265429C126322002 @default.
• W2279265429 hasConceptScore W2279265429C126838900 @default.
• W2279265429 hasConceptScore W2279265429C2776345487 @default.
• W2279265429 hasConceptScore W2279265429C2777819096 @default.
• W2279265429 hasConceptScore W2279265429C2778451229 @default.
• W2279265429 hasConceptScore W2279265429C61434518 @default.
• W2279265429 hasConceptScore W2279265429C71924100 @default.
• W2279265429 hasConceptScore W2279265429C90924648 @default.
• W2279265429 hasIssue "7" @default.
• W2279265429 hasLocation W22792654291 @default.
• W2279265429 hasLocation W22792654292 @default.
• W2279265429 hasOpenAccess W2279265429 @default.
• W2279265429 hasPrimaryLocation W22792654291 @default.
• W2279265429 hasRelatedWork W1979278292 @default.
• W2279265429 hasRelatedWork W200907748 @default.
• W2279265429 hasRelatedWork W2014135440 @default.
• W2279265429 hasRelatedWork W2014435840 @default.
• W2279265429 hasRelatedWork W2056156526 @default.
• W2279265429 hasRelatedWork W2388200098 @default.
• W2279265429 hasRelatedWork W2411319260 @default.
• W2279265429 hasRelatedWork W2413891859 @default.
• W2279265429 hasRelatedWork W2415717579 @default.
• W2279265429 hasRelatedWork W2473703456 @default.
• W2279265429 hasVolume "11" @default.
• W2279265429 isParatext "false" @default.
• W2279265429 isRetracted "false" @default.
• W2279265429 magId "2279265429" @default.
• W2279265429 workType "article" @default.