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- W2279343089 abstract "(6 figures)A transient time-dependent increase in tidal volume (TV) and respiratory rate has been observed as a spirometric loading effect in experiments on 22 decerebrate cats. Respiration was recorded via the impedance pneumograph throughout the entire experiment while tidal volume was measured at intervals of 10–60 min on a spirometer. A total of 233 spirograms was recorded. The mean control tidal volume was 14 ml/kg, followed by an average increase of 30 %, 43 %, 51 %, and 64 % at 30, 60, 90, and 120 sec on the spirometer respectively. Spirometric respiratory rate also increased and as a result instantaneous minute volumes (MV) showed increases up to nearly 400 % of control. Maximal effects occurred within 80 sec reflecting a sequential combination of reflex (via vagal afferents) and chemical (increased CO2) factors reaching a new equilibrium. We also noted a spirometric regularization of previously irregular or periodic (Biot's) breathing. It is apparent that the spirometer introduces small and graded perturbations into respiratory control systems." @default.
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- W2279343089 date "1981-01-01" @default.
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- W2279343089 title "Physiological responses to spirometer load" @default.
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- W2279343089 doi "https://doi.org/10.3109/13813458109082640" @default.
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