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- W2279353607 abstract "in our overall diagnosis and treatment of diseases that implicate the G-protein coupled receptors. Four specific aims have been listed in the grant application: (1). Design and syntheses of agonists (2). Radiosyntheses of agonists (3). In vitro pharmacology of agonists (4). In vivo distribution and pharmacology of labeled derivatives. We have accomplished the syntheses and radiosyntheses of three agonist radiotracers labeled with carbon-11. In vitro and in vivo pharmacological experiments have been accomplished in rats and preliminary PET studies in non-human primates have been carried out. Various accomplishments during the funded years, briefly outlined in this document, have been disseminated by several publications in various journals and presentations in national and international meetings (Society of Nuclear Medicine, Society for Neuroscience and International Symposium on Radiopharmaceutical Chemistry)." @default.
- W2279353607 created "2016-06-24" @default.
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- W2279353607 date "1999-08-01" @default.
- W2279353607 modified "2023-09-26" @default.
- W2279353607 title "Development of dopamine receptor radiopharmaceuticals for the study of neurological and psychiatric disorders. Progress report 1994--1997" @default.
- W2279353607 doi "https://doi.org/10.2172/764610" @default.
- W2279353607 hasPublicationYear "1999" @default.
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