Matches in SemOpenAlex for { <https://semopenalex.org/work/W2279437054> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2279437054 abstract "Many methods for inferring genetic networks have been proposed, but the regulations they infer often include false-positives. Several researchers have attempted to reduce these erroneous regulations by proposing the use of a priori knowledge about the properties of genetic networks such as their sparseness, scale-free structure, and so on. This study focuses on another piece of a priori knowledge, namely, that biochemical networks exhibit hierarchical structures. Based on this idea, we propose an inference approach that uses the hierarchical structure in a target genetic network. To obtain a reasonable hierarchical structure, the first step of the proposed approach is to infer multiple genetic networks from the observed gene expression data. We take this step using an existing method that combines a genetic network inference method with a bootstrap method. The next step is to extract a hierarchical structure from the inferred networks that is consistent with most of the networks. Third, we use the hierarchical structure obtained to assign confidence values to all candidate regulations. Numerical experiments are also performed to demonstrate the effectiveness of using the hierarchical structure in the genetic network inference. The improvement accomplished by the use of the hierarchical structure is small. However, the hierarchical structure could be used to improve the performances of many existing inference methods." @default.
- W2279437054 created "2016-06-24" @default.
- W2279437054 creator A5002937594 @default.
- W2279437054 creator A5019819108 @default.
- W2279437054 creator A5030132908 @default.
- W2279437054 date "2016-02-23" @default.
- W2279437054 modified "2023-10-16" @default.
- W2279437054 title "Genetic Network Inference Using Hierarchical Structure" @default.
- W2279437054 cites W1573150380 @default.
- W2279437054 cites W1963522244 @default.
- W2279437054 cites W2017760855 @default.
- W2279437054 cites W2024060531 @default.
- W2279437054 cites W2076513103 @default.
- W2279437054 cites W2096173332 @default.
- W2279437054 cites W2098740506 @default.
- W2279437054 cites W2100169396 @default.
- W2279437054 cites W2108059946 @default.
- W2279437054 cites W2117897510 @default.
- W2279437054 cites W2119244437 @default.
- W2279437054 cites W2139107718 @default.
- W2279437054 cites W2141239733 @default.
- W2279437054 cites W2143076232 @default.
- W2279437054 cites W2146756876 @default.
- W2279437054 cites W2157082398 @default.
- W2279437054 cites W2159495578 @default.
- W2279437054 cites W2170484057 @default.
- W2279437054 doi "https://doi.org/10.3389/fphys.2016.00057" @default.
- W2279437054 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4763037" @default.
- W2279437054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26941653" @default.
- W2279437054 hasPublicationYear "2016" @default.
- W2279437054 type Work @default.
- W2279437054 sameAs 2279437054 @default.
- W2279437054 citedByCount "4" @default.
- W2279437054 countsByYear W22794370542017 @default.
- W2279437054 countsByYear W22794370542019 @default.
- W2279437054 countsByYear W22794370542023 @default.
- W2279437054 crossrefType "journal-article" @default.
- W2279437054 hasAuthorship W2279437054A5002937594 @default.
- W2279437054 hasAuthorship W2279437054A5019819108 @default.
- W2279437054 hasAuthorship W2279437054A5030132908 @default.
- W2279437054 hasBestOaLocation W22794370541 @default.
- W2279437054 hasConcept C111472728 @default.
- W2279437054 hasConcept C119857082 @default.
- W2279437054 hasConcept C124101348 @default.
- W2279437054 hasConcept C138885662 @default.
- W2279437054 hasConcept C144986985 @default.
- W2279437054 hasConcept C154945302 @default.
- W2279437054 hasConcept C2776214188 @default.
- W2279437054 hasConcept C41008148 @default.
- W2279437054 hasConcept C75553542 @default.
- W2279437054 hasConcept C8880873 @default.
- W2279437054 hasConceptScore W2279437054C111472728 @default.
- W2279437054 hasConceptScore W2279437054C119857082 @default.
- W2279437054 hasConceptScore W2279437054C124101348 @default.
- W2279437054 hasConceptScore W2279437054C138885662 @default.
- W2279437054 hasConceptScore W2279437054C144986985 @default.
- W2279437054 hasConceptScore W2279437054C154945302 @default.
- W2279437054 hasConceptScore W2279437054C2776214188 @default.
- W2279437054 hasConceptScore W2279437054C41008148 @default.
- W2279437054 hasConceptScore W2279437054C75553542 @default.
- W2279437054 hasConceptScore W2279437054C8880873 @default.
- W2279437054 hasFunder F4320334764 @default.
- W2279437054 hasLocation W22794370541 @default.
- W2279437054 hasLocation W22794370542 @default.
- W2279437054 hasLocation W22794370543 @default.
- W2279437054 hasLocation W22794370544 @default.
- W2279437054 hasLocation W22794370545 @default.
- W2279437054 hasOpenAccess W2279437054 @default.
- W2279437054 hasPrimaryLocation W22794370541 @default.
- W2279437054 hasRelatedWork W2373936362 @default.
- W2279437054 hasRelatedWork W2961085424 @default.
- W2279437054 hasRelatedWork W2963058055 @default.
- W2279437054 hasRelatedWork W3046775127 @default.
- W2279437054 hasRelatedWork W3170094116 @default.
- W2279437054 hasRelatedWork W4285260836 @default.
- W2279437054 hasRelatedWork W4286629047 @default.
- W2279437054 hasRelatedWork W4306321456 @default.
- W2279437054 hasRelatedWork W4306674287 @default.
- W2279437054 hasRelatedWork W4224009465 @default.
- W2279437054 hasVolume "7" @default.
- W2279437054 isParatext "false" @default.
- W2279437054 isRetracted "false" @default.
- W2279437054 magId "2279437054" @default.
- W2279437054 workType "article" @default.