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- W2279761797 abstract "OF THESIS EXAMINING MEMORY CONSOLIDATION AND RECONSOLIDATION IN AN APPETITIVE PAVLOVIAN TASK Memory plays an important role in defining how one behaves. The neurobiological mechanisms of memory have been studied extensively in animal models and the NMDA glutamate receptor has been identified to play an important role in the consolidation and reconsolidation of appetitive memories. Certain memories, depending on what was learned, can function differently and can be more difficult to disrupt based on a number of factors. Currently, no study has examined whether or not a rewardpredictive stimulus attributed with incentive value is more difficult to disrupt than a stimulus that functions as a general reward-predictor. To determine the role of the NMDA receptor on memory consolidation with different functioning reward-predictive stimuli rats underwent a Pavlovian conditioned approach, where a post-session NMDA receptor antagonist was administered daily. Furthermore, to determine the role of the NMDA receptor on memory reconsolidation, another set of rats were trained on a Pavlovian conditioned approach task, after training was complete rats were presented with a reward-predictive stimuli followed by an administration of a NMDA receptor antagonist and then re-tested." @default.
- W2279761797 created "2016-06-24" @default.
- W2279761797 creator A5062587888 @default.
- W2279761797 date "2015-01-01" @default.
- W2279761797 modified "2023-09-23" @default.
- W2279761797 title "EXAMINING MEMORY CONSOLIDATION AND RECONSOLIDATION IN AN APPETITIVE PAVLOVIAN TASK" @default.
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- W2279761797 doi "https://doi.org/10.13023/etd.2016.004" @default.
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