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- W2279866352 abstract "258 Objectives The currently accepted minimum administered dose of hepatobiliary radiopharmaceutical is 0.5 mCi/18.5 MBq (Gelfand et al JNM 2011). This study aimed to reduce radiation exposure by lowering the administered radiopharmaceutical dose, while preserving image quality through Enhanced Planar Processing (EPP) software (OncoFlash; Siemens Medical Solutions USA; Petrocelli et al SNM 2006). Methods Studies included 40 patients Results Analysis using General Estimating Equations yielded the following: full dose images-96% acceptable (95% CI: 94%-99%); reduced dose images-76% acceptable (95% CI: 66%-86%); and reduced images with EPP-92% acceptable (95% CI: 87%-97%). The acceptability was significantly higher for both full dose and reduced dose with EPP studies compared to the reduced dose studies (p Conclusions A significant dose reduction with acceptable image quality in these small patients can be achieved with the application of EPP. This study demonstrates the administered dose in this population can be reduced to an average 16%; or from 0.5 mCi to approximately 0.08mCi/2.9MBq. Further refinements to this approach are under way" @default.
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- W2279866352 date "2012-05-01" @default.
- W2279866352 modified "2023-09-27" @default.
- W2279866352 title "Dose reduction in newborns and infants undergoing hepatobiliary scintigraphy" @default.
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