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- W2279882972 abstract "In this study, a new class of K2P blockers, derivatives of tetraethyl ammonium (TEA) with longer alkylic side chains (TnA) is described. Their binding site is determined by site-directed mutagenesis and inside-out giant patch recordings. Experiments on the inhibitory mechanism of TEA derivatives in TREK-1 channels are shown, which reveal that these molecules act as open channel blockers, similar to their mode of action in other channel families like voltage-gated potassium channels." @default.
- W2279882972 created "2016-06-24" @default.
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- W2279882972 date "2015-11-16" @default.
- W2279882972 modified "2023-09-27" @default.
- W2279882972 title "The TPenA binding site in TREK-1 channels" @default.
- W2279882972 hasPublicationYear "2015" @default.
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