FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280197458> ?p ?o ?g. }

• W2280197458 endingPage "72" @default.
• W2280197458 startingPage "64" @default.
• W2280197458 abstract "With the increasing sensitivity of DNA typing methodologies, as well as increasing awareness by law enforcement of the perceived capabilities of DNA typing, complex mixtures consisting of DNA from two or more contributors are increasingly being encountered. However, insufficient research has been conducted to characterize the ability to distinguish a true contributor (TC) from a known non-contributor (KNC) in these complex samples, and under what specific conditions. In order to investigate this question, sets of six 15-locus Caucasian genotype profiles were simulated and used to create mixtures containing 2-5 contributors. Likelihood ratios were computed for various situations, including varying numbers of contributors and unknowns in the evidence profile, as well as comparisons of the evidence profile to TCs and KNCs. This work was intended to illustrate the best-case scenario, in which all alleles from the TC were detected in the simulated evidence samples. Therefore the possibility of drop-out was not modeled in this study. The computer program DNAMIX was then used to compute LRs comparing the evidence profile to TCs and KNCs. This resulted in 140,000 LRs for each of the two scenarios. These complex mixture simulations show that, even when all alleles are detected (i.e. no drop-out), TCs can generate LRs less than 1 across a 15-locus profile. However, this outcome was rare, 7 of 140,000 replicates (0.005%), and associated only with mixtures comprising 5 contributors in which the numerator hypothesis includes one or more unknown contributors. For KNCs, LRs were found to be greater than 1 in a small number of replicates (75 of 140,000 replicates, or 0.05%). These replicates were limited to 4 and 5 person mixtures with 1 or more unknowns in the numerator. Only 5 of these 75 replicates (0.004%) yielded an LR greater than 1,000. Thus, overall, these results imply that the weight of evidence that can be derived from complex mixtures containing up to 5 contributors, under a scenario in which no drop-out is required to explain any of the contributors, is remarkably high. This is a useful benchmark result on top of which to layer the effects of additional factors, such as drop-out, peak height, and other variables." @default.
• W2280197458 created "2016-06-24" @default.
• W2280197458 creator A5066467126 @default.
• W2280197458 creator A5069540945 @default.
• W2280197458 creator A5080359995 @default.
• W2280197458 creator A5088295039 @default.
• W2280197458 date "2016-05-01" @default.
• W2280197458 modified "2023-10-01" @default.
• W2280197458 title "An assessment of the information content of likelihood ratios derived from complex mixtures" @default.
• W2280197458 cites W101128506 @default.
• W2280197458 cites W1711221922 @default.
• W2280197458 cites W1970097290 @default.
• W2280197458 cites W1979252458 @default.
• W2280197458 cites W1995471114 @default.
• W2280197458 cites W2004875711 @default.
• W2280197458 cites W2005416407 @default.
• W2280197458 cites W2014877745 @default.
• W2280197458 cites W2030369315 @default.
• W2280197458 cites W2049619672 @default.
• W2280197458 cites W2051491199 @default.
• W2280197458 cites W2061647941 @default.
• W2280197458 cites W2065861310 @default.
• W2280197458 cites W2068165807 @default.
• W2280197458 cites W2070158494 @default.
• W2280197458 cites W2074642427 @default.
• W2280197458 cites W2078970638 @default.
• W2280197458 cites W2093599316 @default.
• W2280197458 cites W2095864143 @default.
• W2280197458 cites W2097531590 @default.
• W2280197458 cites W2111640582 @default.
• W2280197458 cites W2113214056 @default.
• W2280197458 cites W2114431119 @default.
• W2280197458 cites W2120523528 @default.
• W2280197458 cites W2137030557 @default.
• W2280197458 cites W2142544283 @default.
• W2280197458 cites W2150098756 @default.
• W2280197458 cites W2151343700 @default.
• W2280197458 cites W2157457573 @default.
• W2280197458 cites W2158384452 @default.
• W2280197458 cites W2165516352 @default.
• W2280197458 cites W2169681520 @default.
• W2280197458 cites W3124381111 @default.
• W2280197458 cites W3124699691 @default.
• W2280197458 doi "https://doi.org/10.1016/j.fsigen.2016.01.008" @default.
• W2280197458 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26851613" @default.
• W2280197458 hasPublicationYear "2016" @default.
• W2280197458 type Work @default.
• W2280197458 sameAs 2280197458 @default.
• W2280197458 citedByCount "8" @default.
• W2280197458 countsByYear W22801974582017 @default.
• W2280197458 countsByYear W22801974582018 @default.
• W2280197458 countsByYear W22801974582019 @default.
• W2280197458 countsByYear W22801974582020 @default.
• W2280197458 countsByYear W22801974582022 @default.
• W2280197458 countsByYear W22801974582023 @default.
• W2280197458 crossrefType "journal-article" @default.
• W2280197458 hasAuthorship W2280197458A5066467126 @default.
• W2280197458 hasAuthorship W2280197458A5069540945 @default.
• W2280197458 hasAuthorship W2280197458A5080359995 @default.
• W2280197458 hasAuthorship W2280197458A5088295039 @default.
• W2280197458 hasConcept C104317684 @default.
• W2280197458 hasConcept C105795698 @default.
• W2280197458 hasConcept C135763542 @default.
• W2280197458 hasConcept C162324750 @default.
• W2280197458 hasConcept C180754005 @default.
• W2280197458 hasConcept C2781209916 @default.
• W2280197458 hasConcept C2984949393 @default.
• W2280197458 hasConcept C33923547 @default.
• W2280197458 hasConcept C41008148 @default.
• W2280197458 hasConcept C4249254 @default.
• W2280197458 hasConcept C54355233 @default.
• W2280197458 hasConcept C70721500 @default.
• W2280197458 hasConcept C84597430 @default.
• W2280197458 hasConcept C86803240 @default.
• W2280197458 hasConceptScore W2280197458C104317684 @default.
• W2280197458 hasConceptScore W2280197458C105795698 @default.
• W2280197458 hasConceptScore W2280197458C135763542 @default.
• W2280197458 hasConceptScore W2280197458C162324750 @default.
• W2280197458 hasConceptScore W2280197458C180754005 @default.
• W2280197458 hasConceptScore W2280197458C2781209916 @default.
• W2280197458 hasConceptScore W2280197458C2984949393 @default.
• W2280197458 hasConceptScore W2280197458C33923547 @default.
• W2280197458 hasConceptScore W2280197458C41008148 @default.
• W2280197458 hasConceptScore W2280197458C4249254 @default.
• W2280197458 hasConceptScore W2280197458C54355233 @default.
• W2280197458 hasConceptScore W2280197458C70721500 @default.
• W2280197458 hasConceptScore W2280197458C84597430 @default.
• W2280197458 hasConceptScore W2280197458C86803240 @default.
• W2280197458 hasFunder F4320337430 @default.
• W2280197458 hasLocation W22801974581 @default.
• W2280197458 hasLocation W22801974582 @default.
• W2280197458 hasOpenAccess W2280197458 @default.
• W2280197458 hasPrimaryLocation W22801974581 @default.
• W2280197458 hasRelatedWork W1956762270 @default.
• W2280197458 hasRelatedWork W1971410958 @default.
• W2280197458 hasRelatedWork W2002482473 @default.
• W2280197458 hasRelatedWork W2061630842 @default.
• W2280197458 hasRelatedWork W2105639028 @default.

• next