Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280269174> ?p ?o ?g. }
- W2280269174 endingPage "e0135455" @default.
- W2280269174 startingPage "e0135455" @default.
- W2280269174 abstract "We present a 3D model of the four transmembrane (TM) helical regions of bilitranslocase (BTL), a structurally uncharacterized protein that transports organic anions across the cell membrane. The model was computed by considering helix-helix interactions as primary constraints, using Monte Carlo simulations. The interactions between the TM2 and TM3 segments have been confirmed by Förster resonance energy transfer (FRET) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy, increasing our confidence in the model. Several insights into the BTL transport mechanism were obtained by analyzing the model. For example, the observed cis-trans Leu-Pro peptide bond isomerization in the TM3 fragment may indicate a key conformational change during anion transport by BTL. Our structural model of BTL may facilitate further studies, including drug discovery." @default.
- W2280269174 created "2016-06-24" @default.
- W2280269174 creator A5010616944 @default.
- W2280269174 creator A5017099937 @default.
- W2280269174 creator A5017176365 @default.
- W2280269174 creator A5023769045 @default.
- W2280269174 creator A5028643005 @default.
- W2280269174 creator A5028845140 @default.
- W2280269174 creator A5050870246 @default.
- W2280269174 creator A5052002363 @default.
- W2280269174 creator A5056483461 @default.
- W2280269174 creator A5066002729 @default.
- W2280269174 creator A5069695058 @default.
- W2280269174 creator A5084137608 @default.
- W2280269174 date "2015-08-20" @default.
- W2280269174 modified "2023-10-18" @default.
- W2280269174 title "Structural Model of the Bilitranslocase Transmembrane Domain Supported by NMR and FRET Data" @default.
- W2280269174 cites W1510667834 @default.
- W2280269174 cites W1580122520 @default.
- W2280269174 cites W1619040587 @default.
- W2280269174 cites W1965846687 @default.
- W2280269174 cites W1967671728 @default.
- W2280269174 cites W1967924938 @default.
- W2280269174 cites W1972167596 @default.
- W2280269174 cites W1977610923 @default.
- W2280269174 cites W1978496023 @default.
- W2280269174 cites W1985225270 @default.
- W2280269174 cites W1986800510 @default.
- W2280269174 cites W1999613945 @default.
- W2280269174 cites W2015214828 @default.
- W2280269174 cites W2019768837 @default.
- W2280269174 cites W2022428986 @default.
- W2280269174 cites W2023615714 @default.
- W2280269174 cites W2033323125 @default.
- W2280269174 cites W2034583301 @default.
- W2280269174 cites W2045712605 @default.
- W2280269174 cites W2053530471 @default.
- W2280269174 cites W2056514923 @default.
- W2280269174 cites W2060255617 @default.
- W2280269174 cites W2062903561 @default.
- W2280269174 cites W2076444761 @default.
- W2280269174 cites W2077990714 @default.
- W2280269174 cites W2081578271 @default.
- W2280269174 cites W2088498682 @default.
- W2280269174 cites W2097775366 @default.
- W2280269174 cites W2106648157 @default.
- W2280269174 cites W2109146557 @default.
- W2280269174 cites W2117754160 @default.
- W2280269174 cites W2122510434 @default.
- W2280269174 cites W2139583741 @default.
- W2280269174 cites W2143165274 @default.
- W2280269174 cites W2149138461 @default.
- W2280269174 cites W2154954910 @default.
- W2280269174 doi "https://doi.org/10.1371/journal.pone.0135455" @default.
- W2280269174 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4546402" @default.
- W2280269174 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26291722" @default.
- W2280269174 hasPublicationYear "2015" @default.
- W2280269174 type Work @default.
- W2280269174 sameAs 2280269174 @default.
- W2280269174 citedByCount "7" @default.
- W2280269174 countsByYear W22802691742017 @default.
- W2280269174 countsByYear W22802691742018 @default.
- W2280269174 countsByYear W22802691742019 @default.
- W2280269174 crossrefType "journal-article" @default.
- W2280269174 hasAuthorship W2280269174A5010616944 @default.
- W2280269174 hasAuthorship W2280269174A5017099937 @default.
- W2280269174 hasAuthorship W2280269174A5017176365 @default.
- W2280269174 hasAuthorship W2280269174A5023769045 @default.
- W2280269174 hasAuthorship W2280269174A5028643005 @default.
- W2280269174 hasAuthorship W2280269174A5028845140 @default.
- W2280269174 hasAuthorship W2280269174A5050870246 @default.
- W2280269174 hasAuthorship W2280269174A5052002363 @default.
- W2280269174 hasAuthorship W2280269174A5056483461 @default.
- W2280269174 hasAuthorship W2280269174A5066002729 @default.
- W2280269174 hasAuthorship W2280269174A5069695058 @default.
- W2280269174 hasAuthorship W2280269174A5084137608 @default.
- W2280269174 hasBestOaLocation W22802691741 @default.
- W2280269174 hasConcept C105795698 @default.
- W2280269174 hasConcept C118892022 @default.
- W2280269174 hasConcept C119621388 @default.
- W2280269174 hasConcept C121332964 @default.
- W2280269174 hasConcept C12554922 @default.
- W2280269174 hasConcept C126661725 @default.
- W2280269174 hasConcept C139210041 @default.
- W2280269174 hasConcept C147597530 @default.
- W2280269174 hasConcept C161790260 @default.
- W2280269174 hasConcept C170493617 @default.
- W2280269174 hasConcept C184779094 @default.
- W2280269174 hasConcept C185592680 @default.
- W2280269174 hasConcept C18903297 @default.
- W2280269174 hasConcept C19499675 @default.
- W2280269174 hasConcept C24530287 @default.
- W2280269174 hasConcept C2778530040 @default.
- W2280269174 hasConcept C2779965526 @default.
- W2280269174 hasConcept C32891209 @default.
- W2280269174 hasConcept C33923547 @default.
- W2280269174 hasConcept C41625074 @default.
- W2280269174 hasConcept C55493867 @default.