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• W2280347839 abstract "Full-length L1 elements have been shown to possess, at their 5' end, tandem repeats called A or F types. By sequencing the 5' region of two large L1 copies that did not hybridize to A or F probes, we have identified a new sequence that is found at the 5' end of many L1 elements and that we call V. The element characterized has no 200-bp tandem repetitive structure, and the new 5' sequence is not similar to the A or F sequences. The study of the relationships between the V and L1 sequences has shown that only half of the V (i.e., V-specific 5') sequences in the genome are linked to the 5' end of L1 copies. In related rodent species, a comparative study by Southern blot and PCR analysis of the V sequence suggests that this L1 subfamily has an ancient origin and that V sequence isolated from the remainder of the L1 element has been amplified during the evolution of the mouse genome." @default.
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• W2280347839 date "1992-01-01" @default.
• W2280347839 modified "2023-10-09" @default.
• W2280347839 title "A new 5' sequence associated with mouse L1 elements is representative of a major class of L1 termini." @default.
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• W2280347839 doi "https://doi.org/10.1093/oxfordjournals.molbev.a040707" @default.
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