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- W2280493835 abstract "Tubular pressure oscillations in cortical nephron pairs often synchronize. To determine the extent and duration of synchronization we used laser speckle microscopy on the renal surface of rats. The camera measures changes in surface roughness associated with blood flow changes in 442K pixels at 1/sec. A 15×15 pixel matrix captures one star vessel, and up to 100 star vessels are sampled simultaneously for 30 min or longer. Star vessel locations are identified on the renal surface by ordinary digital microscopy during intravenous dye injection. The digital camera image is overlaid on the time averaged speckle image in Photoshop; star vessel locations are registered on the speckle image. Time series are sampled from the speckle image at each star vessel location. Single star vessel flow changes in response to angiotensin II and acetyl choline mimic those in whole kidney blood flow. The time series were analyzed with wavelet transforms and show oscillations associated with both tubuloglomerular feedback and the myogenic mechanism. Synchronization is present among nephrons but persists for variable periods of time; the size of synchronization clusters also varies with time." @default.
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- W2280493835 date "2010-04-01" @default.
- W2280493835 modified "2023-09-26" @default.
- W2280493835 title "Laser speckle microscopy measurement of arteriolar blood flow in many individual nephrons simultaneously" @default.
- W2280493835 doi "https://doi.org/10.1096/fasebj.24.1_supplement.1059.26" @default.
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