FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280639138> ?p ?o ?g. }

• W2280639138 endingPage "104" @default.
• W2280639138 startingPage "92" @default.
• W2280639138 abstract "The loading characteristics of recombinant Staphyloccocus aureus protein A (rSPA) on polypropylene (PP) capillary-channeled polymer (C-CP) fibers were investigated through breakthrough curves and frontal analysis. The dynamic adsorption data was fit to various isotherm models to assess the possible mode of rSPA-PP fiber adsorption. Among them, the Langmuir-linear model fit the experimental data best, suggesting a two-stage mechanism of adsorption. The first stage involves the formation of a monolayer coverage, which follows the Langmuir isotherm. When the adsorbate concentration increases, solute starts to adsorb onto the already adsorbed layer, following a linear adsorption response. The relationship between the rSPA loading and flow rate and column length was also investigated. These two parameters are related through the residence time of rSPA in the column. It was determined that loading at the flow rate of 0.5 mL min−1 (∼28 mm s−1) with a 1 × 10−5 M (0.5 mg mL−1) rSPA feed concentration on a 30-cm (0.762 mm i.d.) column could conveniently produce a reasonable binding capacity of rSPA on PP surface within only 6 min. Under those conditions, the rSPA binding at 50% breakthrough was found to be ∼2.1 mg g−1 fiber. Operation of the rSPA-modified columns across ten complete processing cycles using clean-in-place conditions (including urea, guanidine HCl, and NaOH) commonly used in the bioprocessing industry allows assessment of the robustness of the rSPA capture layers. In all cases, the robustness was quite good, with the relative responses providing insights to the rSPA/PP surface structure." @default.
• W2280639138 created "2016-06-24" @default.
• W2280639138 creator A5006563075 @default.
• W2280639138 creator A5011021504 @default.
• W2280639138 creator A5058395601 @default.
• W2280639138 creator A5072237279 @default.
• W2280639138 date "2016-03-01" @default.
• W2280639138 modified "2023-10-01" @default.
• W2280639138 title "Evaluation of loading characteristics and IgG binding performance of Staphylococcal protein A on polypropylene capillary-channeled polymer fibers" @default.
• W2280639138 cites W1968825081 @default.
• W2280639138 cites W1971270351 @default.
• W2280639138 cites W1973177703 @default.
• W2280639138 cites W1974758945 @default.
• W2280639138 cites W1974916290 @default.
• W2280639138 cites W1976720082 @default.
• W2280639138 cites W1976740575 @default.
• W2280639138 cites W1977733114 @default.
• W2280639138 cites W1978889503 @default.
• W2280639138 cites W1979330161 @default.
• W2280639138 cites W1985238965 @default.
• W2280639138 cites W1985638030 @default.
• W2280639138 cites W1985676128 @default.
• W2280639138 cites W1986113254 @default.
• W2280639138 cites W1998045081 @default.
• W2280639138 cites W1998924068 @default.
• W2280639138 cites W2001244036 @default.
• W2280639138 cites W2002985712 @default.
• W2280639138 cites W2005209180 @default.
• W2280639138 cites W2007083328 @default.
• W2280639138 cites W2007469546 @default.
• W2280639138 cites W2012887210 @default.
• W2280639138 cites W2015150213 @default.
• W2280639138 cites W2015815857 @default.
• W2280639138 cites W2016133866 @default.
• W2280639138 cites W2022814920 @default.
• W2280639138 cites W2025412034 @default.
• W2280639138 cites W2027075143 @default.
• W2280639138 cites W2030822098 @default.
• W2280639138 cites W2038478327 @default.
• W2280639138 cites W2042284290 @default.
• W2280639138 cites W2043807407 @default.
• W2280639138 cites W2045703351 @default.
• W2280639138 cites W2051809212 @default.
• W2280639138 cites W2067328736 @default.
• W2280639138 cites W2070210111 @default.
• W2280639138 cites W2071678409 @default.
• W2280639138 cites W2074840722 @default.
• W2280639138 cites W2075221747 @default.
• W2280639138 cites W2077500683 @default.
• W2280639138 cites W2079602405 @default.
• W2280639138 cites W2081019229 @default.
• W2280639138 cites W2095871606 @default.
• W2280639138 cites W2097732780 @default.
• W2280639138 cites W2100508150 @default.
• W2280639138 cites W2118540273 @default.
• W2280639138 cites W2118708855 @default.
• W2280639138 cites W2127070615 @default.
• W2280639138 cites W2138062257 @default.
• W2280639138 cites W2146704789 @default.
• W2280639138 cites W2152495597 @default.
• W2280639138 cites W2156456192 @default.
• W2280639138 cites W2332000621 @default.
• W2280639138 cites W2917973694 @default.
• W2280639138 cites W33426820 @default.
• W2280639138 cites W4313377124 @default.
• W2280639138 cites W976937304 @default.
• W2280639138 doi "https://doi.org/10.1016/j.jchromb.2016.02.024" @default.
• W2280639138 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26919444" @default.
• W2280639138 hasPublicationYear "2016" @default.
• W2280639138 type Work @default.
• W2280639138 sameAs 2280639138 @default.
• W2280639138 citedByCount "17" @default.
• W2280639138 countsByYear W22806391382016 @default.
• W2280639138 countsByYear W22806391382017 @default.
• W2280639138 countsByYear W22806391382018 @default.
• W2280639138 countsByYear W22806391382019 @default.
• W2280639138 countsByYear W22806391382020 @default.
• W2280639138 countsByYear W22806391382021 @default.
• W2280639138 countsByYear W22806391382022 @default.
• W2280639138 countsByYear W22806391382023 @default.
• W2280639138 crossrefType "journal-article" @default.
• W2280639138 hasAuthorship W2280639138A5006563075 @default.
• W2280639138 hasAuthorship W2280639138A5011021504 @default.
• W2280639138 hasAuthorship W2280639138A5058395601 @default.
• W2280639138 hasAuthorship W2280639138A5072237279 @default.
• W2280639138 hasBestOaLocation W22806391381 @default.
• W2280639138 hasConcept C113196181 @default.
• W2280639138 hasConcept C121332964 @default.
• W2280639138 hasConcept C12143843 @default.
• W2280639138 hasConcept C150394285 @default.
• W2280639138 hasConcept C159985019 @default.
• W2280639138 hasConcept C172120300 @default.
• W2280639138 hasConcept C178790620 @default.
• W2280639138 hasConcept C185592680 @default.
• W2280639138 hasConcept C192562407 @default.
• W2280639138 hasConcept C196806460 @default.
• W2280639138 hasConcept C2777973245 @default.
• W2280639138 hasConcept C43617362 @default.

• next