Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280646545> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2280646545 endingPage "1039" @default.
- W2280646545 startingPage "1032" @default.
- W2280646545 abstract "The haemodynamic effects of a single dose of intravenous molsidomine were assessed in 12 patients with severe coronary disease. The investigation was carried out at rest during angina induced by pacing and after molsidomine during pacing at the rate at which angina had been produced. During angina, left ventricular systolic and end-diastolic pressure rose, left ventricular stroke work fell and coronary flow and myocardial oxygen consumption increased by 58.3% above the control levels. After the administration of molsidomine, atrial stimulation was not followed by angina and there were no significant changes in systolic blood pressure. Left ventricular end-diastolic pressure fell sharply and coronary flow and myocardial oxygen consumption were only 38% and 33% higher, respectively, than the control levels. The beneficial effects of molsidomine in ischaemic heart disease, therefore, are the result of peripheral vasodilation which, by reducing the preload and after load, lowers the oxygen requirements of the myocardium and thus increase the threshold for angina. A direct action on the coronary network can not be excluded but if such an action does exist it must be very small in the light of the marked systemic effect." @default.
- W2280646545 created "2016-06-24" @default.
- W2280646545 creator A5016889433 @default.
- W2280646545 creator A5030738208 @default.
- W2280646545 creator A5050305540 @default.
- W2280646545 creator A5052433567 @default.
- W2280646545 creator A5062220462 @default.
- W2280646545 creator A5070607140 @default.
- W2280646545 creator A5087128549 @default.
- W2280646545 date "1985-12-01" @default.
- W2280646545 modified "2023-09-27" @default.
- W2280646545 title "Haemodynamic effects of molsidomine in patients with severe chronic coronary disease" @default.
- W2280646545 doi "https://doi.org/10.1093/oxfordjournals.eurheartj.a061806" @default.
- W2280646545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3841658" @default.
- W2280646545 hasPublicationYear "1985" @default.
- W2280646545 type Work @default.
- W2280646545 sameAs 2280646545 @default.
- W2280646545 citedByCount "2" @default.
- W2280646545 crossrefType "journal-article" @default.
- W2280646545 hasAuthorship W2280646545A5016889433 @default.
- W2280646545 hasAuthorship W2280646545A5030738208 @default.
- W2280646545 hasAuthorship W2280646545A5050305540 @default.
- W2280646545 hasAuthorship W2280646545A5052433567 @default.
- W2280646545 hasAuthorship W2280646545A5062220462 @default.
- W2280646545 hasAuthorship W2280646545A5070607140 @default.
- W2280646545 hasAuthorship W2280646545A5087128549 @default.
- W2280646545 hasConcept C120770815 @default.
- W2280646545 hasConcept C123576724 @default.
- W2280646545 hasConcept C126322002 @default.
- W2280646545 hasConcept C164705383 @default.
- W2280646545 hasConcept C178853913 @default.
- W2280646545 hasConcept C2777953023 @default.
- W2280646545 hasConcept C2778425758 @default.
- W2280646545 hasConcept C2780685332 @default.
- W2280646545 hasConcept C2780773033 @default.
- W2280646545 hasConcept C2909076160 @default.
- W2280646545 hasConcept C42219234 @default.
- W2280646545 hasConcept C48277249 @default.
- W2280646545 hasConcept C500558357 @default.
- W2280646545 hasConcept C519581460 @default.
- W2280646545 hasConcept C71924100 @default.
- W2280646545 hasConcept C80461066 @default.
- W2280646545 hasConcept C84393581 @default.
- W2280646545 hasConceptScore W2280646545C120770815 @default.
- W2280646545 hasConceptScore W2280646545C123576724 @default.
- W2280646545 hasConceptScore W2280646545C126322002 @default.
- W2280646545 hasConceptScore W2280646545C164705383 @default.
- W2280646545 hasConceptScore W2280646545C178853913 @default.
- W2280646545 hasConceptScore W2280646545C2777953023 @default.
- W2280646545 hasConceptScore W2280646545C2778425758 @default.
- W2280646545 hasConceptScore W2280646545C2780685332 @default.
- W2280646545 hasConceptScore W2280646545C2780773033 @default.
- W2280646545 hasConceptScore W2280646545C2909076160 @default.
- W2280646545 hasConceptScore W2280646545C42219234 @default.
- W2280646545 hasConceptScore W2280646545C48277249 @default.
- W2280646545 hasConceptScore W2280646545C500558357 @default.
- W2280646545 hasConceptScore W2280646545C519581460 @default.
- W2280646545 hasConceptScore W2280646545C71924100 @default.
- W2280646545 hasConceptScore W2280646545C80461066 @default.
- W2280646545 hasConceptScore W2280646545C84393581 @default.
- W2280646545 hasIssue "12" @default.
- W2280646545 hasLocation W22806465451 @default.
- W2280646545 hasLocation W22806465452 @default.
- W2280646545 hasOpenAccess W2280646545 @default.
- W2280646545 hasPrimaryLocation W22806465451 @default.
- W2280646545 hasRelatedWork W1493903379 @default.
- W2280646545 hasRelatedWork W2018204093 @default.
- W2280646545 hasRelatedWork W2280646545 @default.
- W2280646545 hasRelatedWork W231827625 @default.
- W2280646545 hasRelatedWork W2332949356 @default.
- W2280646545 hasRelatedWork W2415403403 @default.
- W2280646545 hasRelatedWork W2470256234 @default.
- W2280646545 hasRelatedWork W35845135 @default.
- W2280646545 hasRelatedWork W42011023 @default.
- W2280646545 hasRelatedWork W4293578471 @default.
- W2280646545 hasVolume "6" @default.
- W2280646545 isParatext "false" @default.
- W2280646545 isRetracted "false" @default.
- W2280646545 magId "2280646545" @default.
- W2280646545 workType "article" @default.