FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280753316> ?p ?o ?g. }

• W2280753316 endingPage "108" @default.
• W2280753316 startingPage "95" @default.
• W2280753316 abstract "Retinoic acid, a potent transcriptional activator, is believed to be an important factor in the regulation of vertebrate development (for review see Eichele, 1989; Gudas, 1994; Tabin, 1991; Boncinelli, et al., 1991; Kessel and Gruss, 1991a; 1991b; Kessel, 1992; Gudas, 1994). Retinaldehyde dehydrogenases catalyze the last step of retinoic acid synthesis and these enzymes are known to belong to a larger aldehyde dehydrogenases family (for review see Petersen and Lindahl, 1997). The distribution of endogenous retinaldehyde dehydrogenases in the developing animal sets up patterns of endogenous gradients of retinoic acid which modulate gene transcription and has been suggested to aid in establishing the developmental framework which organizes both the segmented body plan and the structure of individual organs (for review see Kessel and Gruss, 1991a; 1991b; Marsh-Armstrong, et al., 1995; 1994; Hyatt, et al., 1992; Watterson, et al., 1954; McCaffery, et al., 1991; 1992; McCaffery and Dräger, 1993; 1994; 1995; Dräger and McCaffery, 1995). This is clearly seen during the anteroposterior patterning of the trunk (Marsh-Armstrong, et al., 1994) in the Zebrafish, Danio rerio, in which an endogenous gradient of retinaldehyde dehydrogenase creates a matching gradient of retinoic acid along the anterior-to-posterior axis of the trunk, such as the pectoral, pelvic and anal fin. This occurs during the critical periods in embryogenesis when axial and appendicular structures are forming. Transcriptional regulation of the family of homeobox (Hox) genes, which are normally expressed in sequence along the length of the trunk (for review see Krumlauf, 1994; Krumlauf, et al., 1993; Kenyon, 1994; McGinnis and Krumlauf, 1992; Kessel and Gruss, 1991; Kessel, 1992), has been shown to be activated during development by retinoic acid in a sequential order, with 3′ end genes being activated more rapidly after exposure to retinoic acid, and 5′ end genes responding at progressively later times following retinoic acid exposure (for reviews see Krumlauf, 1994; Krumlauf, et al., 1993; Kenyon, 1994; McGinnis and Krumlauf, 1992; Kessel and Gruss, 1991; Kessel, 1992). Normal patterns of developmental gene expression, such as in the case of Hox genes, are altered in conditions of exogenous retinoic acid excess and deficiency (for review see Eichele, 1989; Gudas, 1994; Tabin, 1991; Boncinelli, et al., 1991; Kessel and Gruss, 1991a; 1991b; Kessel andGruss, 1991; Kessel, 1992; Langston and Gudas, 1994), resulting in “homeotic” transformations, which change the normal order of vertebrae (changing the phenotype of anterior vertebra to that of posterior vertebrae), or the neurons in the hindbrain (Manns and Fritzsch, 1992)." @default.
• W2280753316 created "2016-06-24" @default.
• W2280753316 creator A5037680649 @default.
• W2280753316 creator A5068752287 @default.
• W2280753316 creator A5088083061 @default.
• W2280753316 date "1996-01-01" @default.
• W2280753316 modified "2023-10-16" @default.
• W2280753316 title "Sex Differences in Endogenous Retinoid Release in the Post-Embryonic Spinal Cord of the Western Mosquitofish, Gambusia affinis affinis" @default.
• W2280753316 cites W109201434 @default.
• W2280753316 cites W117813152 @default.
• W2280753316 cites W1510855520 @default.
• W2280753316 cites W1599391997 @default.
• W2280753316 cites W1607326348 @default.
• W2280753316 cites W1850838207 @default.
• W2280753316 cites W1880270297 @default.
• W2280753316 cites W1905627141 @default.
• W2280753316 cites W1966764838 @default.
• W2280753316 cites W1981699260 @default.
• W2280753316 cites W1990278701 @default.
• W2280753316 cites W1996306915 @default.
• W2280753316 cites W2006877541 @default.
• W2280753316 cites W2007084552 @default.
• W2280753316 cites W2008668441 @default.
• W2280753316 cites W2009851083 @default.
• W2280753316 cites W2011932624 @default.
• W2280753316 cites W2013126973 @default.
• W2280753316 cites W2048249977 @default.
• W2280753316 cites W2051388483 @default.
• W2280753316 cites W2052553158 @default.
• W2280753316 cites W2068911324 @default.
• W2280753316 cites W2072352047 @default.
• W2280753316 cites W2074658209 @default.
• W2280753316 cites W2080444658 @default.
• W2280753316 cites W2080556349 @default.
• W2280753316 cites W2090298881 @default.
• W2280753316 cites W2092047281 @default.
• W2280753316 cites W2125161058 @default.
• W2280753316 cites W2139556530 @default.
• W2280753316 cites W2162169187 @default.
• W2280753316 cites W2286464757 @default.
• W2280753316 cites W238009640 @default.
• W2280753316 cites W2800808901 @default.
• W2280753316 cites W4255617001 @default.
• W2280753316 doi "https://doi.org/10.1007/978-1-4615-5871-2_12" @default.
• W2280753316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9059611" @default.
• W2280753316 hasPublicationYear "1996" @default.
• W2280753316 type Work @default.
• W2280753316 sameAs 2280753316 @default.
• W2280753316 citedByCount "4" @default.
• W2280753316 countsByYear W22807533162016 @default.
• W2280753316 crossrefType "book-chapter" @default.
• W2280753316 hasAuthorship W2280753316A5037680649 @default.
• W2280753316 hasAuthorship W2280753316A5068752287 @default.
• W2280753316 hasAuthorship W2280753316A5088083061 @default.
• W2280753316 hasConcept C104317684 @default.
• W2280753316 hasConcept C105702510 @default.
• W2280753316 hasConcept C121587040 @default.
• W2280753316 hasConcept C134018914 @default.
• W2280753316 hasConcept C16613235 @default.
• W2280753316 hasConcept C2776878037 @default.
• W2280753316 hasConcept C2777075493 @default.
• W2280753316 hasConcept C2780384893 @default.
• W2280753316 hasConcept C2781121885 @default.
• W2280753316 hasConcept C54355233 @default.
• W2280753316 hasConcept C86339819 @default.
• W2280753316 hasConcept C86803240 @default.
• W2280753316 hasConcept C95444343 @default.
• W2280753316 hasConceptScore W2280753316C104317684 @default.
• W2280753316 hasConceptScore W2280753316C105702510 @default.
• W2280753316 hasConceptScore W2280753316C121587040 @default.
• W2280753316 hasConceptScore W2280753316C134018914 @default.
• W2280753316 hasConceptScore W2280753316C16613235 @default.
• W2280753316 hasConceptScore W2280753316C2776878037 @default.
• W2280753316 hasConceptScore W2280753316C2777075493 @default.
• W2280753316 hasConceptScore W2280753316C2780384893 @default.
• W2280753316 hasConceptScore W2280753316C2781121885 @default.
• W2280753316 hasConceptScore W2280753316C54355233 @default.
• W2280753316 hasConceptScore W2280753316C86339819 @default.
• W2280753316 hasConceptScore W2280753316C86803240 @default.
• W2280753316 hasConceptScore W2280753316C95444343 @default.
• W2280753316 hasLocation W22807533161 @default.
• W2280753316 hasLocation W22807533162 @default.
• W2280753316 hasOpenAccess W2280753316 @default.
• W2280753316 hasPrimaryLocation W22807533161 @default.
• W2280753316 hasRelatedWork W1992684640 @default.
• W2280753316 hasRelatedWork W24064635 @default.
• W2280753316 hasRelatedWork W2922730069 @default.
• W2280753316 hasRelatedWork W2938575486 @default.
• W2280753316 hasRelatedWork W2947128474 @default.
• W2280753316 hasRelatedWork W3025909797 @default.
• W2280753316 hasRelatedWork W3109425268 @default.
• W2280753316 hasRelatedWork W4237600267 @default.
• W2280753316 hasRelatedWork W4245153001 @default.
• W2280753316 hasRelatedWork W4256528904 @default.
• W2280753316 isParatext "false" @default.
• W2280753316 isRetracted "false" @default.
• W2280753316 magId "2280753316" @default.
• W2280753316 workType "book-chapter" @default.