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- W2280884805 abstract "ABSTRACT Purpose: To investigate the orbital invasion and metastatic pattern in retinoblastoma, and to analyze the correlation with other pathologic and prognostic factors. Methods: Pathologic and admission records of 45 patients with a pathologically confirmed diagnosis of retinoblastoma during the past 20 years were reviewed. Clinical risk factors and pathologic findings were analyzed for association with tumor invasion/metastasis using chi-square, Fisher's exact, and Student's t tests. Results: Clinical risk factors such as exophthalmos, cataract, and pseudohypopyon were significantly correlated with tumor invasion/metastasis. The pathologic finding of choroid involvement was highly predictive of tumor invasion/metastasis. Delayed enucleation (>3 months) also was significantly correlated with tumor invasion/metastasis. Conclusion: Tumor invasion/metastasis is strongly associated with various ocular, pathologic, and treatment outcome factors. Identification of these risk factors may help plan treatment regimens. Journal of Pediatric Ophthalmology and Strabismus 2001 ;38:1 66-171." @default.
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- W2280884805 date "2001-05-01" @default.
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- W2280884805 title "Clinicopathologic Factors Related to Metastasis in Retinoblastoma" @default.
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- W2280884805 doi "https://doi.org/10.3928/0191-3913-20010501-11" @default.
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