FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2280957704> ?p ?o ?g. }

• W2280957704 endingPage "218" @default.
• W2280957704 startingPage "209" @default.
• W2280957704 abstract "Adherence to biologic disease-modifying antirheumatic drugs (bDMARDs) among patients with rheumatoid arthritis (RA) is often suboptimal in routine clinical practice. Low or nonadherence can reduce the effectiveness of bDMARD therapies.To evaluate filling of newly prescribed initial bDMARDs for the treatment of RA and evaluate potential for characterizing treatment decisions and patient outcomes.In this retrospective cohort analysis, patients aged ≥ 18 years with an RA diagnosis (ICD-9-CM code 714.xx) were selected from a de-identified database of clinical information from the Electronic Health Record (EHR; Humedica) database linked to health care claims (Optum) from commercial and Medicare Advantage health plans (2007-2013). The first biologic prescription date in EHR was the index date. Patients were categorized as filling the prescription within 30 days (early fillers), 31-180 days (late fillers), or not at all within 180 days (nonfillers) of index date.Of 373 patients meeting inclusion criteria, 170 (45.6%), 59 (15.8%), and 144 (38.6%) were categorized as early fillers, late fillers, and nonfillers, respectively. Most prescriptions were written or ordered for tumor necrosis factor inhibitors (88.7%). Compared with late and nonfillers, early fillers were younger and more likely to be female, with higher pain scores (among those reporting pain scores) and RA severity scores pre-index, and filled more prescriptions for any reason pre-index. More nonfillers (66.0%) were Medicare patients than early (17.7%) and late (35.6%) fillers. During days 0-30 post-index, conventional synthetic DMARD use was greatest for early fillers (45.9%) and lowest among nonfillers (24.3%); however, during days 31-180 post-index, the proportion was highest for late fillers (61.0%) and lowest for nonfillers (35.4%). Of early fillers, 12.9% did not fill/receive a bDMARD after 30 days. Only 23 patients had pre/post-index pain scores, and 47 patients had a rationale for stopping or not filling a bDMARD. In patients with pharmacy and medical coverage for 180 days post-index, early fillers had greater RA-related pharmacy and medical resource use and costs than late and nonfillers combined.These findings confirm a high rate of primary nonadherence to bDMARDs among patients with RA." @default.
• W2280957704 created "2016-06-24" @default.
• W2280957704 creator A5004596365 @default.
• W2280957704 creator A5014651532 @default.
• W2280957704 creator A5044917302 @default.
• W2280957704 creator A5061716516 @default.
• W2280957704 creator A5064863811 @default.
• W2280957704 creator A5076338304 @default.
• W2280957704 date "2016-03-01" @default.
• W2280957704 modified "2023-10-11" @default.
• W2280957704 title "Primary Nonadherence, Associated Clinical Outcomes, and Health Care Resource Use Among Patients with Rheumatoid Arthritis Prescribed Treatment with Injectable Biologic Disease-Modifying Antirheumatic Drugs" @default.
• W2280957704 cites W1551539224 @default.
• W2280957704 cites W159282500 @default.
• W2280957704 cites W1761300068 @default.
• W2280957704 cites W1983081844 @default.
• W2280957704 cites W1994433204 @default.
• W2280957704 cites W2000119601 @default.
• W2280957704 cites W2004084979 @default.
• W2280957704 cites W2007346566 @default.
• W2280957704 cites W2024209817 @default.
• W2280957704 cites W2029116114 @default.
• W2280957704 cites W2029896549 @default.
• W2280957704 cites W2038593306 @default.
• W2280957704 cites W2045685449 @default.
• W2280957704 cites W2048447144 @default.
• W2280957704 cites W2056070464 @default.
• W2280957704 cites W2079159057 @default.
• W2280957704 cites W2119729506 @default.
• W2280957704 cites W2120393706 @default.
• W2280957704 cites W2122356011 @default.
• W2280957704 cites W2126525702 @default.
• W2280957704 cites W2138780114 @default.
• W2280957704 cites W2139415330 @default.
• W2280957704 cites W2149553288 @default.
• W2280957704 cites W2418625878 @default.
• W2280957704 cites W4210768724 @default.
• W2280957704 doi "https://doi.org/10.18553/jmcp.2016.22.3.209" @default.
• W2280957704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27003550" @default.
• W2280957704 hasPublicationYear "2016" @default.
• W2280957704 type Work @default.
• W2280957704 sameAs 2280957704 @default.
• W2280957704 citedByCount "25" @default.
• W2280957704 countsByYear W22809577042016 @default.
• W2280957704 countsByYear W22809577042017 @default.
• W2280957704 countsByYear W22809577042018 @default.
• W2280957704 countsByYear W22809577042019 @default.
• W2280957704 countsByYear W22809577042020 @default.
• W2280957704 countsByYear W22809577042021 @default.
• W2280957704 countsByYear W22809577042022 @default.
• W2280957704 countsByYear W22809577042023 @default.
• W2280957704 crossrefType "journal-article" @default.
• W2280957704 hasAuthorship W2280957704A5004596365 @default.
• W2280957704 hasAuthorship W2280957704A5014651532 @default.
• W2280957704 hasAuthorship W2280957704A5044917302 @default.
• W2280957704 hasAuthorship W2280957704A5061716516 @default.
• W2280957704 hasAuthorship W2280957704A5064863811 @default.
• W2280957704 hasAuthorship W2280957704A5076338304 @default.
• W2280957704 hasBestOaLocation W22809577041 @default.
• W2280957704 hasConcept C126322002 @default.
• W2280957704 hasConcept C167135981 @default.
• W2280957704 hasConcept C1862650 @default.
• W2280957704 hasConcept C2426938 @default.
• W2280957704 hasConcept C2777575956 @default.
• W2280957704 hasConcept C2908564923 @default.
• W2280957704 hasConcept C2908647359 @default.
• W2280957704 hasConcept C2909063479 @default.
• W2280957704 hasConcept C45827449 @default.
• W2280957704 hasConcept C71924100 @default.
• W2280957704 hasConcept C72563966 @default.
• W2280957704 hasConcept C98274493 @default.
• W2280957704 hasConcept C99454951 @default.
• W2280957704 hasConceptScore W2280957704C126322002 @default.
• W2280957704 hasConceptScore W2280957704C167135981 @default.
• W2280957704 hasConceptScore W2280957704C1862650 @default.
• W2280957704 hasConceptScore W2280957704C2426938 @default.
• W2280957704 hasConceptScore W2280957704C2777575956 @default.
• W2280957704 hasConceptScore W2280957704C2908564923 @default.
• W2280957704 hasConceptScore W2280957704C2908647359 @default.
• W2280957704 hasConceptScore W2280957704C2909063479 @default.
• W2280957704 hasConceptScore W2280957704C45827449 @default.
• W2280957704 hasConceptScore W2280957704C71924100 @default.
• W2280957704 hasConceptScore W2280957704C72563966 @default.
• W2280957704 hasConceptScore W2280957704C98274493 @default.
• W2280957704 hasConceptScore W2280957704C99454951 @default.
• W2280957704 hasIssue "3" @default.
• W2280957704 hasLocation W22809577041 @default.
• W2280957704 hasLocation W22809577042 @default.
• W2280957704 hasOpenAccess W2280957704 @default.
• W2280957704 hasPrimaryLocation W22809577041 @default.
• W2280957704 hasRelatedWork W1551539224 @default.
• W2280957704 hasRelatedWork W1868536540 @default.
• W2280957704 hasRelatedWork W2030388214 @default.
• W2280957704 hasRelatedWork W2077703058 @default.
• W2280957704 hasRelatedWork W2131913726 @default.
• W2280957704 hasRelatedWork W2404217170 @default.
• W2280957704 hasRelatedWork W2474945707 @default.
• W2280957704 hasRelatedWork W3021018229 @default.
• W2280957704 hasRelatedWork W3164831646 @default.

• next