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- W2281213805 abstract "16593 Background: Chemotherapy treatment has been recently introduced for patients diagnosed with advanced cervical tumors that were previously treated exclusively with radiotherapy. MRI is the main imaging tool to evaluate pelvic response and predict therapeutic results and survival. Purpose: To determine if tumor volume and corporal invasion presence in Magnetic Resonance staging exam could be predictor of outcomes in advanced cervix carcinomas. Materials and Methods: Using RECIST criteria, 56 women diagnosed with advanced cervical tumors were studied prospectively. Patients underwent pelvic Magnetic Resonance at staging for measured tumor volume and identify tumoral corporal invasion. All the patients received the same treatment and underwent the same exam protocol with Phased-Array and endovenous contrast. RECIST criteria were applied so that the patients undergoing the combined treatment could have follow-up parameters. We correlated Magnetic Resonance parameters with outcomes after all treatment. Results: Tumor volume and corporal invasion proved to be excellent parameters to predict outcomes after combined chemo and radiotherapy. Patients who presented corporal invasion at the staging exam showed a worse prognostic even though they had complete response after brachytherapy. Also patients with tumor volume more than 100 cm3 had a bad response. Conclusion: Tumor volume and corporal invasion at staging Magnetic Resonance showed to be good parameters for predict outcomes in advanced cervical carcinomas. No significant financial relationships to disclose." @default.
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- W2281213805 date "2008-05-20" @default.
- W2281213805 modified "2023-09-29" @default.
- W2281213805 title "MRI parameters as a predictor of outcomes in advanced cervical carcinomas" @default.
- W2281213805 doi "https://doi.org/10.1200/jco.2008.26.15_suppl.16593" @default.
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