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• W2281316503 abstract "Introduction:Bacterial plaque is the most important factor in periodontal diseases and plaque control is effective in the preventionof periodontitis. Mechanical plaque control is the most reliable method in plaque reduction but because insufficientmechanical plaque control is usually performed by most patients, chemical plaque control beside mechanical plaquecontrol is more desirable.Several chemical agents for chemical plaque control are used and chlorhexidine is the most effective agent inchemical plaque control and it causes plaque and gingival inflammation reduction. However, chlorhexidine sideeffects, the most common of which being tooth staining and dorsal tongue staining, are the main factors ininadequate compliance among patients. Scientists suggest the use of oxidating mouthrinses such as hydrogenperoxide and carbamide peroxide for reduction of chlorhexidine staining. The purpose in this study was to comparethe induced stain and plaque and gingivitis reduction between chlorhexidine alone and hydrogen peroxide as adjunctto chlorhexidine.Materials & Methods:In this interventional Study, 30 patients with mild to moderate gingivitis referred to periodontic clinic of mashhaddental school (26 males, 4 females), were randomly assigned in a double–blind, 2 group parallel design study. At thebeginning of the study, all subjects received scaling and root planing and polishing. After two weeks, PI, GI, andGBI were examined. Gluconate chlorhexidine 0.2% mouhrinse was prescribed for control group to be used for 30seconds twice a day for 14 days. Subjects in the test group rinsed their mouth with hydrogen peroxide 1.5% for 30seconds prior to chlorhexidine use twice a day for 14 days.During the study, the patients refrained from brushing. After 14 days, PI, GI, GBI and stain index were recordedagain for both groups.The data were statistically analysed by t-test using SPSS 10 software.Results:PI scores for both groups were approximately equal at the end of study. GI and GBI scores were also approximatelyequal at the end of the study however, reduction in these scores was slightly greater for the control group. Theresidual inflammation in the test group might be attributed to the used of hydrogen peroxide. The considerablereduction in both severity and extend of staining score in body region in test group was significantly lower thancontrol group but there was no significant difference between two groups in stain severity scores in gingival region.Conclusion:We conclude that use of hydrogen peroxide prior to chlorhexidine may cause significant reduction in tooth staining.Moreover, hydrogen peroxide does not have negative effects on plaque and gingivitis reduction ability ofchlorhexidine.Key words:Mouthrinse, chlorhexidine, hydrogen peroxide, plaque, gingivitis." @default.
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• W2281316503 date "2006-01-01" @default.
• W2281316503 modified "2023-09-26" @default.
• W2281316503 title "EFFECTS OF COMBINED USE OF HYDROGEN PEROXIDE AND CHLORHEXIDINE MOUTH RINSES ON GINGIVITIS, PLAQUE AND TOOTH STAINING" @default.
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