Matches in SemOpenAlex for { <https://semopenalex.org/work/W2281367134> ?p ?o ?g. }
Showing items 1 to 80 of
80
with 100 items per page.
- W2281367134 endingPage "9" @default.
- W2281367134 startingPage "1" @default.
- W2281367134 abstract "The organ distribution and toxicity of p-DCB were compared in rats after either inhalation or oral administration. Male F344 rats were exposed to 500 or 125 ppm for 24 hr in a whole body inhalation chamber (H and L groups) or received a single dose of 300 mg/kg by gavage (PO group). The concentrations of p-DCB in the serum, liver, kidney and fatty tissues were measured by gas chromatography at intervals during and up to 24 hr after the treatment. Peak serum values for the L and H groups were lower than in the PO animals, but the organ/serum distribution ratios of p-DCB tended to be higher, in some cases markedly, in rats receiving the inhalation treatment. Significant increases in the levels of blood urea nitrogen, hepatic glutamic oxaloacetic transaminase and glutamic pyruvate transaminase and significant decreases in the levels of serum total cholesterol were observed only in the inhalation groups. Microscopically, the appearance of numerous eosinophilic droplets, together with swelling and desquamation of the proximal tubular epithelium of the kidney was especially noteworthy in H and L p-DCB treated groups. Thus, both biochemical and histopathological abnormalities induced by p-DCB were more pronounced in rats administered the compound by the inhalation route." @default.
- W2281367134 created "2016-06-24" @default.
- W2281367134 creator A5002004328 @default.
- W2281367134 creator A5008274536 @default.
- W2281367134 creator A5010881015 @default.
- W2281367134 creator A5044571161 @default.
- W2281367134 creator A5051464322 @default.
- W2281367134 creator A5052777563 @default.
- W2281367134 creator A5063381098 @default.
- W2281367134 creator A5089934507 @default.
- W2281367134 date "1989-12-01" @default.
- W2281367134 modified "2023-09-23" @default.
- W2281367134 title "Comparison of the toxicity of p-dichlorobenzene (p-DCB) administered to male F344 rats orally or by the inhalation route." @default.
- W2281367134 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2640063" @default.
- W2281367134 hasPublicationYear "1989" @default.
- W2281367134 type Work @default.
- W2281367134 sameAs 2281367134 @default.
- W2281367134 citedByCount "4" @default.
- W2281367134 crossrefType "journal-article" @default.
- W2281367134 hasAuthorship W2281367134A5002004328 @default.
- W2281367134 hasAuthorship W2281367134A5008274536 @default.
- W2281367134 hasAuthorship W2281367134A5010881015 @default.
- W2281367134 hasAuthorship W2281367134A5044571161 @default.
- W2281367134 hasAuthorship W2281367134A5051464322 @default.
- W2281367134 hasAuthorship W2281367134A5052777563 @default.
- W2281367134 hasAuthorship W2281367134A5063381098 @default.
- W2281367134 hasAuthorship W2281367134A5089934507 @default.
- W2281367134 hasConcept C126322002 @default.
- W2281367134 hasConcept C134018914 @default.
- W2281367134 hasConcept C181199279 @default.
- W2281367134 hasConcept C185592680 @default.
- W2281367134 hasConcept C195289149 @default.
- W2281367134 hasConcept C2776877979 @default.
- W2281367134 hasConcept C2776954882 @default.
- W2281367134 hasConcept C2778176769 @default.
- W2281367134 hasConcept C2779777708 @default.
- W2281367134 hasConcept C2780091579 @default.
- W2281367134 hasConcept C2780365088 @default.
- W2281367134 hasConcept C29730261 @default.
- W2281367134 hasConcept C42219234 @default.
- W2281367134 hasConcept C55493867 @default.
- W2281367134 hasConcept C71924100 @default.
- W2281367134 hasConcept C98274493 @default.
- W2281367134 hasConceptScore W2281367134C126322002 @default.
- W2281367134 hasConceptScore W2281367134C134018914 @default.
- W2281367134 hasConceptScore W2281367134C181199279 @default.
- W2281367134 hasConceptScore W2281367134C185592680 @default.
- W2281367134 hasConceptScore W2281367134C195289149 @default.
- W2281367134 hasConceptScore W2281367134C2776877979 @default.
- W2281367134 hasConceptScore W2281367134C2776954882 @default.
- W2281367134 hasConceptScore W2281367134C2778176769 @default.
- W2281367134 hasConceptScore W2281367134C2779777708 @default.
- W2281367134 hasConceptScore W2281367134C2780091579 @default.
- W2281367134 hasConceptScore W2281367134C2780365088 @default.
- W2281367134 hasConceptScore W2281367134C29730261 @default.
- W2281367134 hasConceptScore W2281367134C42219234 @default.
- W2281367134 hasConceptScore W2281367134C55493867 @default.
- W2281367134 hasConceptScore W2281367134C71924100 @default.
- W2281367134 hasConceptScore W2281367134C98274493 @default.
- W2281367134 hasIssue "1-4" @default.
- W2281367134 hasLocation W22813671341 @default.
- W2281367134 hasOpenAccess W2281367134 @default.
- W2281367134 hasPrimaryLocation W22813671341 @default.
- W2281367134 hasRelatedWork W1980339709 @default.
- W2281367134 hasRelatedWork W2018920030 @default.
- W2281367134 hasRelatedWork W2020959757 @default.
- W2281367134 hasRelatedWork W2042033030 @default.
- W2281367134 hasRelatedWork W2044943066 @default.
- W2281367134 hasRelatedWork W2070511355 @default.
- W2281367134 hasRelatedWork W2082456910 @default.
- W2281367134 hasRelatedWork W2281367134 @default.
- W2281367134 hasRelatedWork W2400445066 @default.
- W2281367134 hasRelatedWork W4214585610 @default.
- W2281367134 hasVolume "36" @default.
- W2281367134 isParatext "false" @default.
- W2281367134 isRetracted "false" @default.
- W2281367134 magId "2281367134" @default.
- W2281367134 workType "article" @default.