Matches in SemOpenAlex for { <https://semopenalex.org/work/W2281593912> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2281593912 startingPage "240" @default.
- W2281593912 abstract "(S)-Ibuprofen acid is classified as a non-steroidal anti-inflammatory drug (NSAID) that is well-known to be useful in treating mild to moderate pain, fever and inflammation. The production of this optically pure compound poses a major challenge for the pharmaceutical industry. In the present technology, a hollow fiber membrane reactor (HFMR) system is innovatively designed to carry out dynamic kinetic resolution (DKR) of racemic Ibuprofen ester. DKR is described as a chiral separation technique that incorporates the classic kinetic resolution (KR) with in situ racemization. The operation principle of the HFMR is simple and environmental friendly. It combines the reaction, product separation and by-product recovery in a single unit. The design of the HMFR was clearly discussed in this article. The HFMR performance was studied by varying the important process parameters such as effect of alcohols, substrate and base concentration as well as the flow rates for both lumen and shell side. The HFMR gave product enantiomeric excess of 98.5% and 99% conversion at molar ratio of 1:3 with respect to the substrate and alcohol, 50 mM of base concentration, shell and lumen loop flow rates of 80 and 200 ml min-1 respectively. The application of enzymatic biphasic membrane reactor for DKR provides a green and efficient way for obtaining the high purity product without any generation of by product." @default.
- W2281593912 created "2016-06-24" @default.
- W2281593912 creator A5006205891 @default.
- W2281593912 creator A5007190902 @default.
- W2281593912 creator A5043019954 @default.
- W2281593912 date "2012-01-01" @default.
- W2281593912 modified "2023-09-23" @default.
- W2281593912 title "Production of optically pure (s)-ibuprofen acid via enzymatic dynamic kinetic resolution in hollow fiber membrane reactor" @default.
- W2281593912 cites W1963731585 @default.
- W2281593912 cites W1973991515 @default.
- W2281593912 cites W1993664341 @default.
- W2281593912 cites W1997144789 @default.
- W2281593912 cites W1997447150 @default.
- W2281593912 cites W1998564252 @default.
- W2281593912 cites W2021407562 @default.
- W2281593912 cites W2034838377 @default.
- W2281593912 cites W2048726938 @default.
- W2281593912 cites W2063026295 @default.
- W2281593912 cites W2064511485 @default.
- W2281593912 cites W2069961270 @default.
- W2281593912 cites W2323030487 @default.
- W2281593912 hasPublicationYear "2012" @default.
- W2281593912 type Work @default.
- W2281593912 sameAs 2281593912 @default.
- W2281593912 citedByCount "0" @default.
- W2281593912 crossrefType "journal-article" @default.
- W2281593912 hasAuthorship W2281593912A5006205891 @default.
- W2281593912 hasAuthorship W2281593912A5007190902 @default.
- W2281593912 hasAuthorship W2281593912A5043019954 @default.
- W2281593912 hasConcept C111368507 @default.
- W2281593912 hasConcept C127313418 @default.
- W2281593912 hasConcept C146686406 @default.
- W2281593912 hasConcept C161790260 @default.
- W2281593912 hasConcept C178790620 @default.
- W2281593912 hasConcept C185592680 @default.
- W2281593912 hasConcept C2777289219 @default.
- W2281593912 hasConcept C2778260969 @default.
- W2281593912 hasConcept C2779944601 @default.
- W2281593912 hasConcept C28173026 @default.
- W2281593912 hasConcept C3141732 @default.
- W2281593912 hasConcept C41625074 @default.
- W2281593912 hasConcept C43617362 @default.
- W2281593912 hasConcept C519885992 @default.
- W2281593912 hasConcept C55493867 @default.
- W2281593912 hasConcept C60002323 @default.
- W2281593912 hasConcept C71924100 @default.
- W2281593912 hasConcept C97488330 @default.
- W2281593912 hasConcept C98274493 @default.
- W2281593912 hasConceptScore W2281593912C111368507 @default.
- W2281593912 hasConceptScore W2281593912C127313418 @default.
- W2281593912 hasConceptScore W2281593912C146686406 @default.
- W2281593912 hasConceptScore W2281593912C161790260 @default.
- W2281593912 hasConceptScore W2281593912C178790620 @default.
- W2281593912 hasConceptScore W2281593912C185592680 @default.
- W2281593912 hasConceptScore W2281593912C2777289219 @default.
- W2281593912 hasConceptScore W2281593912C2778260969 @default.
- W2281593912 hasConceptScore W2281593912C2779944601 @default.
- W2281593912 hasConceptScore W2281593912C28173026 @default.
- W2281593912 hasConceptScore W2281593912C3141732 @default.
- W2281593912 hasConceptScore W2281593912C41625074 @default.
- W2281593912 hasConceptScore W2281593912C43617362 @default.
- W2281593912 hasConceptScore W2281593912C519885992 @default.
- W2281593912 hasConceptScore W2281593912C55493867 @default.
- W2281593912 hasConceptScore W2281593912C60002323 @default.
- W2281593912 hasConceptScore W2281593912C71924100 @default.
- W2281593912 hasConceptScore W2281593912C97488330 @default.
- W2281593912 hasConceptScore W2281593912C98274493 @default.
- W2281593912 hasLocation W22815939121 @default.
- W2281593912 hasOpenAccess W2281593912 @default.
- W2281593912 hasPrimaryLocation W22815939121 @default.
- W2281593912 hasRelatedWork W1990921347 @default.
- W2281593912 hasRelatedWork W1997447150 @default.
- W2281593912 hasRelatedWork W1998564252 @default.
- W2281593912 hasRelatedWork W2002942559 @default.
- W2281593912 hasRelatedWork W2009658869 @default.
- W2281593912 hasRelatedWork W2011257053 @default.
- W2281593912 hasRelatedWork W2057664437 @default.
- W2281593912 hasRelatedWork W2066937306 @default.
- W2281593912 hasRelatedWork W2067968313 @default.
- W2281593912 hasRelatedWork W2082173401 @default.
- W2281593912 hasRelatedWork W2089158621 @default.
- W2281593912 hasRelatedWork W2126661364 @default.
- W2281593912 hasRelatedWork W2150709908 @default.
- W2281593912 hasRelatedWork W2300440326 @default.
- W2281593912 hasRelatedWork W2374090064 @default.
- W2281593912 hasRelatedWork W2593125253 @default.
- W2281593912 hasRelatedWork W2611762532 @default.
- W2281593912 hasRelatedWork W2614903392 @default.
- W2281593912 hasRelatedWork W831392655 @default.
- W2281593912 hasRelatedWork W2527133364 @default.
- W2281593912 isParatext "false" @default.
- W2281593912 isRetracted "false" @default.
- W2281593912 magId "2281593912" @default.
- W2281593912 workType "article" @default.