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- W2281623154 abstract "To determine the incidence of congenital syphilis in Lusaka 200 infants consecutively admitted to a neonatal intensive care unit over a 4-week period in 1981 were screened serologically for syphilitic infection. A definite diagnosis of syphilis was made in 3 infants while a probable diagnosis based on suspicious clinical signs was made in an additional 12 infants for a total incidence of 7.5% in this series. Prominent clinical features in these 15 infants included hepatosplenomegaly mucocutaneous lesions and jaundice. Typical radiological changes in long bones were noted in all 15 infants. 10 of the 15 infants were premature and 2 had asphyxia. 9 of the infants with congenital syphilis died subsequently. All the 13 mothers of these infants had received antenatal care but screening for syphilis was done on only 5 women none of whom received treatment. Clinical signs of early infectious syphilis were present in 6 mothers and darkfield examinations were positive in 3 women. During this same period 18 stillborn infants delivered at the hospital were seroreactive for syphilis bringing the number of perinatal deaths attributable to syphilis to 27. Diagnosis and management of early congenital syphilis is a problem because only a small number of infants show signs of infection at birth. Preventive efforts during pregnancy should be supplemented by cord screening at birth as well as the routine screening for syphilis of all infants brought to the hospital with illnesses and all premature infants." @default.
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- W2281623154 date "1982-06-01" @default.
- W2281623154 modified "2023-10-18" @default.
- W2281623154 title "Congenital syphilis in Lusaka--III. Incidence in the neonatal intensive-care unit." @default.
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