FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2282997761> ?p ?o ?g. }

• W2282997761 endingPage "92" @default.
• W2282997761 startingPage "22382" @default.
• W2282997761 abstract "Sex-determining region Y-box protein 2 (Sox2), an embryonic transcription factor located at chromosome 3q26.33, has been frequently demonstrated to be an important prognostic marker for various tumors, including breast cancer. However, its clinicopathological role in breast cancer has not been fully elucidated. To derive a more precise evaluation, we here performed a meta-analysis focusing on the association between Sox2 expression and various clinicopathological characteristics of breast cancer. Relevant publications were identified and retrieved using PubMed, Embase, Cochrane Library, Web of Science, Chinese National Knowledge Infrastructure, and Chinese Biomedical databases. Ten studies with a total of 1713 patients with breast cancer were included in our meta-analysis. Reported odds ratios (OR) and the corresponding 95% confidence intervals (95% CI) were pooled to assess the strengths of the analyzed associations. Our results revealed significant positive associations between Sox2 expression and increased tumor size (pooled OR=2.61, 95% CI=1.91-3.58), histological grade (pooled OR=2.28, 95% CI=1.72-3.03), lymph node metastasis (pooled OR=4.17, 95% CI=1.20-14.45), and the highly aggressive triple-negative phenotype (pooled OR=2.64, 95% CI=1.11-6.29). However, no associations were observed for TNM stage and estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 statuses. Overall, the results of this meta-analysis indicate that Sox2 may be considered as a prognostic marker for breast cancer. More well-designed studies with larger sample sizes are warranted to clarify the prognostic significance of Sox2 in breast cancer." @default.
• W2282997761 created "2016-06-24" @default.
• W2282997761 creator A5006299161 @default.
• W2282997761 creator A5027475930 @default.
• W2282997761 creator A5050580197 @default.
• W2282997761 creator A5055299862 @default.
• W2282997761 creator A5073783148 @default.
• W2282997761 creator A5076477740 @default.
• W2282997761 date "2015-01-01" @default.
• W2282997761 modified "2023-10-18" @default.
• W2282997761 title "Clinicopathological significance of Sox2 expression in patients with breast cancer: a meta-analysis." @default.
• W2282997761 cites W1974008072 @default.
• W2282997761 cites W2001530424 @default.
• W2282997761 cites W2017980240 @default.
• W2282997761 cites W2035222904 @default.
• W2282997761 cites W2043765395 @default.
• W2282997761 cites W2044303467 @default.
• W2282997761 cites W2046769573 @default.
• W2282997761 cites W2058675403 @default.
• W2282997761 cites W2073759231 @default.
• W2282997761 cites W2074406343 @default.
• W2282997761 cites W2077841029 @default.
• W2282997761 cites W2079777624 @default.
• W2282997761 cites W2081620427 @default.
• W2282997761 cites W2083984673 @default.
• W2282997761 cites W2106787323 @default.
• W2282997761 cites W2125435699 @default.
• W2282997761 cites W2126930838 @default.
• W2282997761 cites W2130396542 @default.
• W2282997761 cites W2134852288 @default.
• W2282997761 cites W2142721942 @default.
• W2282997761 cites W2143188916 @default.
• W2282997761 cites W2160064770 @default.
• W2282997761 cites W2162582079 @default.
• W2282997761 cites W2167281518 @default.
• W2282997761 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4730004" @default.
• W2282997761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26885218" @default.
• W2282997761 hasPublicationYear "2015" @default.
• W2282997761 type Work @default.
• W2282997761 sameAs 2282997761 @default.
• W2282997761 citedByCount "6" @default.
• W2282997761 countsByYear W22829977612017 @default.
• W2282997761 countsByYear W22829977612018 @default.
• W2282997761 countsByYear W22829977612021 @default.
• W2282997761 countsByYear W22829977612022 @default.
• W2282997761 crossrefType "journal-article" @default.
• W2282997761 hasAuthorship W2282997761A5006299161 @default.
• W2282997761 hasAuthorship W2282997761A5027475930 @default.
• W2282997761 hasAuthorship W2282997761A5050580197 @default.
• W2282997761 hasAuthorship W2282997761A5055299862 @default.
• W2282997761 hasAuthorship W2282997761A5073783148 @default.
• W2282997761 hasAuthorship W2282997761A5076477740 @default.
• W2282997761 hasConcept C104317684 @default.
• W2282997761 hasConcept C121608353 @default.
• W2282997761 hasConcept C126322002 @default.
• W2282997761 hasConcept C143998085 @default.
• W2282997761 hasConcept C156957248 @default.
• W2282997761 hasConcept C2776478404 @default.
• W2282997761 hasConcept C2777933648 @default.
• W2282997761 hasConcept C44249647 @default.
• W2282997761 hasConcept C530470458 @default.
• W2282997761 hasConcept C55493867 @default.
• W2282997761 hasConcept C71924100 @default.
• W2282997761 hasConcept C84606932 @default.
• W2282997761 hasConcept C86339819 @default.
• W2282997761 hasConcept C86803240 @default.
• W2282997761 hasConcept C95190672 @default.
• W2282997761 hasConceptScore W2282997761C104317684 @default.
• W2282997761 hasConceptScore W2282997761C121608353 @default.
• W2282997761 hasConceptScore W2282997761C126322002 @default.
• W2282997761 hasConceptScore W2282997761C143998085 @default.
• W2282997761 hasConceptScore W2282997761C156957248 @default.
• W2282997761 hasConceptScore W2282997761C2776478404 @default.
• W2282997761 hasConceptScore W2282997761C2777933648 @default.
• W2282997761 hasConceptScore W2282997761C44249647 @default.
• W2282997761 hasConceptScore W2282997761C530470458 @default.
• W2282997761 hasConceptScore W2282997761C55493867 @default.
• W2282997761 hasConceptScore W2282997761C71924100 @default.
• W2282997761 hasConceptScore W2282997761C84606932 @default.
• W2282997761 hasConceptScore W2282997761C86339819 @default.
• W2282997761 hasConceptScore W2282997761C86803240 @default.
• W2282997761 hasConceptScore W2282997761C95190672 @default.
• W2282997761 hasIssue "12" @default.
• W2282997761 hasLocation W22829977611 @default.
• W2282997761 hasOpenAccess W2282997761 @default.
• W2282997761 hasPrimaryLocation W22829977611 @default.
• W2282997761 hasRelatedWork W2014943083 @default.
• W2282997761 hasRelatedWork W2071995032 @default.
• W2282997761 hasRelatedWork W2082392604 @default.
• W2282997761 hasRelatedWork W2328387903 @default.
• W2282997761 hasRelatedWork W2531767482 @default.
• W2282997761 hasRelatedWork W2739409155 @default.
• W2282997761 hasRelatedWork W2793980702 @default.
• W2282997761 hasRelatedWork W3116417372 @default.
• W2282997761 hasRelatedWork W3124218749 @default.
• W2282997761 hasRelatedWork W3150135412 @default.
• W2282997761 hasVolume "8" @default.
• W2282997761 isParatext "false" @default.

• next