Matches in SemOpenAlex for { <https://semopenalex.org/work/W2283256024> ?p ?o ?g. }
- W2283256024 endingPage "411" @default.
- W2283256024 startingPage "405" @default.
- W2283256024 abstract "Mucus glycoproteins from newborn and adult rat small intestine were radiolabelled in vivo with Na2 35SO4 and isolated from mucosal homogenates by using Sepharose 4B column chromatography followed by CsCl-density-gradient centrifugation. Non-covalently bound proteins, lipids and nucleic acids were not detected in the purified glycoproteins. Amino acid, carbohydrate and sulphate compositions were similar to chemical compositions reported for other intestinal mucus glycoproteins, as were sedimentation properties. There were, however, important differences in the chemical and physical characteristics of the mucus glycoproteins from newborn and adult animals. The buoyant density in CsCl was higher for the glycoproteins from newborn rats (1.55 g/ml versus 1.47 g/ml). On sodium dodecyl sulphate/polyacrylamide/agarose-gel electrophoresis, the glycoprotein from newborn rats had a greater mobility than the adult-rat sample. Although both preparations had similar general amino acid compositions, variations were observed for individual amino acids. The total protein content was greater in the glycoprotein from newborn animals (27%, w/w, versus 18%, w/w). The molar ratio of carbohydrate to protein was less in the newborn, primarily owing to a decreased fucose and N-acetylgalactosamine content. Comparison of the molar ratio of fucose and sialic acid to galactose for both glycoproteins demonstrated a reciprocal relationship similar to that described by Dische [(1963) Ann. N.Y. Acad. Sci. 106, 259-270]. The sulphate content was greater in the glycoprotein from newborn rats (5.5%, w/w, versus 0.9%, w/w). Both had similar sedimentation coefficients in a dissociative solvent. These results suggest an age-related difference in the types of mucus glycoproteins synthesized by small intestine." @default.
- W2283256024 created "2016-06-24" @default.
- W2283256024 creator A5004986770 @default.
- W2283256024 creator A5047903848 @default.
- W2283256024 creator A5064361102 @default.
- W2283256024 creator A5089246659 @default.
- W2283256024 date "1983-11-01" @default.
- W2283256024 modified "2023-10-15" @default.
- W2283256024 title "Age-related changes in chemical composition and physical properties of mucus glycoproteins from rat small intestine" @default.
- W2283256024 cites W1595907664 @default.
- W2283256024 cites W1602739921 @default.
- W2283256024 cites W16331706 @default.
- W2283256024 cites W1801703436 @default.
- W2283256024 cites W1801813548 @default.
- W2283256024 cites W1829896530 @default.
- W2283256024 cites W1992664836 @default.
- W2283256024 cites W2013368290 @default.
- W2283256024 cites W2020428008 @default.
- W2283256024 cites W2023623448 @default.
- W2283256024 cites W2034884916 @default.
- W2283256024 cites W2040411188 @default.
- W2283256024 cites W2063732289 @default.
- W2283256024 cites W2072973802 @default.
- W2283256024 cites W2123031849 @default.
- W2283256024 cites W2128643396 @default.
- W2283256024 cites W2188749728 @default.
- W2283256024 cites W2414154159 @default.
- W2283256024 cites W53929440 @default.
- W2283256024 doi "https://doi.org/10.1042/bj2150405" @default.
- W2283256024 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1152409" @default.
- W2283256024 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6651768" @default.
- W2283256024 hasPublicationYear "1983" @default.
- W2283256024 type Work @default.
- W2283256024 sameAs 2283256024 @default.
- W2283256024 citedByCount "95" @default.
- W2283256024 countsByYear W22832560242012 @default.
- W2283256024 countsByYear W22832560242013 @default.
- W2283256024 countsByYear W22832560242014 @default.
- W2283256024 countsByYear W22832560242015 @default.
- W2283256024 countsByYear W22832560242016 @default.
- W2283256024 countsByYear W22832560242017 @default.
- W2283256024 countsByYear W22832560242018 @default.
- W2283256024 countsByYear W22832560242019 @default.
- W2283256024 countsByYear W22832560242021 @default.
- W2283256024 countsByYear W22832560242022 @default.
- W2283256024 crossrefType "journal-article" @default.
- W2283256024 hasAuthorship W2283256024A5004986770 @default.
- W2283256024 hasAuthorship W2283256024A5047903848 @default.
- W2283256024 hasAuthorship W2283256024A5064361102 @default.
- W2283256024 hasAuthorship W2283256024A5089246659 @default.
- W2283256024 hasBestOaLocation W22832560242 @default.
- W2283256024 hasConcept C108625454 @default.
- W2283256024 hasConcept C132946820 @default.
- W2283256024 hasConcept C181199279 @default.
- W2283256024 hasConcept C185592680 @default.
- W2283256024 hasConcept C18903297 @default.
- W2283256024 hasConcept C2776841590 @default.
- W2283256024 hasConcept C2777312293 @default.
- W2283256024 hasConcept C2778977261 @default.
- W2283256024 hasConcept C2779881004 @default.
- W2283256024 hasConcept C2780115458 @default.
- W2283256024 hasConcept C43617362 @default.
- W2283256024 hasConcept C515207424 @default.
- W2283256024 hasConcept C55493867 @default.
- W2283256024 hasConcept C7623868 @default.
- W2283256024 hasConcept C86803240 @default.
- W2283256024 hasConceptScore W2283256024C108625454 @default.
- W2283256024 hasConceptScore W2283256024C132946820 @default.
- W2283256024 hasConceptScore W2283256024C181199279 @default.
- W2283256024 hasConceptScore W2283256024C185592680 @default.
- W2283256024 hasConceptScore W2283256024C18903297 @default.
- W2283256024 hasConceptScore W2283256024C2776841590 @default.
- W2283256024 hasConceptScore W2283256024C2777312293 @default.
- W2283256024 hasConceptScore W2283256024C2778977261 @default.
- W2283256024 hasConceptScore W2283256024C2779881004 @default.
- W2283256024 hasConceptScore W2283256024C2780115458 @default.
- W2283256024 hasConceptScore W2283256024C43617362 @default.
- W2283256024 hasConceptScore W2283256024C515207424 @default.
- W2283256024 hasConceptScore W2283256024C55493867 @default.
- W2283256024 hasConceptScore W2283256024C7623868 @default.
- W2283256024 hasConceptScore W2283256024C86803240 @default.
- W2283256024 hasIssue "2" @default.
- W2283256024 hasLocation W22832560241 @default.
- W2283256024 hasLocation W22832560242 @default.
- W2283256024 hasLocation W22832560243 @default.
- W2283256024 hasLocation W22832560244 @default.
- W2283256024 hasOpenAccess W2283256024 @default.
- W2283256024 hasPrimaryLocation W22832560241 @default.
- W2283256024 hasRelatedWork W1986427399 @default.
- W2283256024 hasRelatedWork W2051929873 @default.
- W2283256024 hasRelatedWork W2084630612 @default.
- W2283256024 hasRelatedWork W2134935519 @default.
- W2283256024 hasRelatedWork W2169726602 @default.
- W2283256024 hasRelatedWork W2397987193 @default.
- W2283256024 hasRelatedWork W2399595124 @default.
- W2283256024 hasRelatedWork W2409991977 @default.
- W2283256024 hasRelatedWork W2416920511 @default.
- W2283256024 hasRelatedWork W2466207899 @default.