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- W2283280863 abstract "An exact quantitative evaluation method of autonomic dysfunction in Parkinson's disease (PD) for everyday clinical use has not been developed yet. The aim of this study was to evaluate autonomic cardiovascular regulation in mild and advanced stages of PD with the use of heart rate variability (HRV) examination. Twenty-five patients entered the study and passed short-term HRV examination in supine position with metronome-controlled breathing f = 0.33 Hz. The following parameters of power spectral analysis were evaluated: Total Power (TP; ms 2 ), Low Frequency Power (0.04-0.14 Hz; Power LF; ms 2 ), High Frequency Power (0.15-0.4 Hz; Power HF; ms ) in the group of patients with a higher mean HY T test). The change of LF/HF was not statistically significant. The short-term examination of heart rate variability fulfils the criteria for test objectivity, reproducibility, reliability, and validity. We proved a higher impairment of autonomic cardiovascular regulation in the group of PD patients with advanced PD (H&Y = 2.3) than in mild PD (H&Y = 1.3). Short-term HRV examination is also sensitive enough to be used for comparison of the difference of autonomic dysfunction corresponding to the change of impairment by 1 grade in H&Y score." @default.
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- W2283280863 date "2008-01-01" @default.
- W2283280863 modified "2023-09-22" @default.
- W2283280863 title "AUTONOMIC DYSFUNCTION AND PROGRESSION OF PARKINSON'S DISEASE" @default.
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