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- W2283291297 abstract "化学物质在机体内诱导产生活性氧自由基能攻击:DNA,主要生成8-羟基鸟嘌呤(7,8.dihydr0-8-oxoguanine,8-oxo-Gua),它可导致DNA链空间构象的改变,在DNA复制过程中引起G:C-T:A颠换,形成点突变,该点突变被认为与肿瘤的发生发展、机体细胞的老化和某些退行性疾病均有密切的关系[1]。" @default.
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- W2283291297 date "2009-05-01" @default.
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- W2283291297 title "[Preliminary investigation on DNA oxidation impairment repair enzymes MTH1, OGG1 and UTYH as well as their interactions]." @default.
- W2283291297 doi "https://doi.org/10.3760/cma.j.issn.1001-9391.2009.05.022" @default.
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