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- W2283307490 abstract "THE EFFECT OF BUTTER, NATURALLY ENRICHED WITH TRANS-10, CIS-12 CONJUGATED LINOLEIC ACID, ON INSULIN RESISTANCE AND INFLAMMATION IN HIGH FAT-FED RODENTS Amanda Stefanson Advisor: University of Guelph, 2013 Professor D C Wright This study was conducted to evaluate dietary CLAt10,c12, given the studies showing that supplemental doses has a negative impact on insulin resistance. To that end, we produced a 60% high fat diet composed of butter produced from milk collected from dairy cows suffering from subacute ruminal acidosis (SARA) – a condition that can sometimes result from the dairy industry production practice of feeding a high grain, low forage diet to milk-producing cows. This butter represents the most CLAt10,c12-enriched source of naturally occurring CLAt10,c12 for humans. We compared the effects of the high CLAt10,c12 butter against a commercially available butter in a high fat diet-induced rodent model of insulin resistance. After 8 weeks, whole body glucose homeostasis was evaluated along with markers of inflammation, indicated by mitogen-activated protein kinase (MAPK) activation." @default.
- W2283307490 created "2016-06-24" @default.
- W2283307490 creator A5042755297 @default.
- W2283307490 date "2013-09-17" @default.
- W2283307490 modified "2023-09-27" @default.
- W2283307490 title "The effect of butter, naturally enriched with trans-10, cis-12 conjugated linoleic acid, on insulin resistance and inflammation in high fat-fed rodents" @default.
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