Matches in SemOpenAlex for { <https://semopenalex.org/work/W2283525086> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2283525086 endingPage "42" @default.
- W2283525086 startingPage "34" @default.
- W2283525086 abstract "To investigate the effects on lung function of IV magnesium in acute exacerbations of COPD (AECOPD), when given in conjunction with standard bronchodilator therapy.This was a pilot study to a randomised, double-blinded, placebo-controlled trial. 30 patients presenting to ED with AECOPD were included. In addition to standard bronchodilator therapy, 17 patients were given saline, and 13 received 2 g of magnesium sulphate intravenously. Spirometry was carried out at presentation (TA), after initial standard bronchodilator therapy (TB) and immediately (T0), at 60 minutes (T60) and 120 minutes (T120) after trial drug infusion. Primary outcomes were percentage change in FEV1 and FVC at T0, T60 and T120. Secondary outcomes were admission rates, length of stay and requirement for NIV or mechanical ventilation. Trial registration (ANZCTR), ACTRN12613000837729.Greater improvements were seen in FEV1 at T0, T60 and T120 compared to TB in magnesium group (at T120, mean percentage change in FEV1 was 27.07% with magnesium versus 11.39% in the placebo group, 95%CI 3.7 to 27.7, p=0.01). Similar significantly greater improvements were noted with FVC in the magnesium group, compared to TB.IV magnesium sulphate used as an adjunct therapy to standard bronchodilators in AECOPD presenting to ED may improve lung function in the short term." @default.
- W2283525086 created "2016-06-24" @default.
- W2283525086 creator A5007597515 @default.
- W2283525086 creator A5008981808 @default.
- W2283525086 creator A5035830172 @default.
- W2283525086 creator A5052192445 @default.
- W2283525086 creator A5073234813 @default.
- W2283525086 creator A5074345525 @default.
- W2283525086 creator A5084189538 @default.
- W2283525086 creator A5089263345 @default.
- W2283525086 date "2015-11-20" @default.
- W2283525086 modified "2023-09-26" @default.
- W2283525086 title "Intravenous magnesium sulphate as an adjuvant therapy in acute exacerbations of chronic obstructive pulmonary disease: a single centre, randomised, double-blinded, parallel group, placebo-controlled trial: a pilot study." @default.
- W2283525086 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26905985" @default.
- W2283525086 hasPublicationYear "2015" @default.
- W2283525086 type Work @default.
- W2283525086 sameAs 2283525086 @default.
- W2283525086 citedByCount "4" @default.
- W2283525086 countsByYear W22835250862021 @default.
- W2283525086 countsByYear W22835250862022 @default.
- W2283525086 crossrefType "journal-article" @default.
- W2283525086 hasAuthorship W2283525086A5007597515 @default.
- W2283525086 hasAuthorship W2283525086A5008981808 @default.
- W2283525086 hasAuthorship W2283525086A5035830172 @default.
- W2283525086 hasAuthorship W2283525086A5052192445 @default.
- W2283525086 hasAuthorship W2283525086A5073234813 @default.
- W2283525086 hasAuthorship W2283525086A5074345525 @default.
- W2283525086 hasAuthorship W2283525086A5084189538 @default.
- W2283525086 hasAuthorship W2283525086A5089263345 @default.
- W2283525086 hasConcept C126322002 @default.
- W2283525086 hasConcept C142724271 @default.
- W2283525086 hasConcept C168563851 @default.
- W2283525086 hasConcept C1862650 @default.
- W2283525086 hasConcept C204787440 @default.
- W2283525086 hasConcept C27081682 @default.
- W2283525086 hasConcept C2776042228 @default.
- W2283525086 hasConcept C2776780178 @default.
- W2283525086 hasConcept C2780333948 @default.
- W2283525086 hasConcept C2781018748 @default.
- W2283525086 hasConcept C42219234 @default.
- W2283525086 hasConcept C71924100 @default.
- W2283525086 hasConceptScore W2283525086C126322002 @default.
- W2283525086 hasConceptScore W2283525086C142724271 @default.
- W2283525086 hasConceptScore W2283525086C168563851 @default.
- W2283525086 hasConceptScore W2283525086C1862650 @default.
- W2283525086 hasConceptScore W2283525086C204787440 @default.
- W2283525086 hasConceptScore W2283525086C27081682 @default.
- W2283525086 hasConceptScore W2283525086C2776042228 @default.
- W2283525086 hasConceptScore W2283525086C2776780178 @default.
- W2283525086 hasConceptScore W2283525086C2780333948 @default.
- W2283525086 hasConceptScore W2283525086C2781018748 @default.
- W2283525086 hasConceptScore W2283525086C42219234 @default.
- W2283525086 hasConceptScore W2283525086C71924100 @default.
- W2283525086 hasIssue "1425" @default.
- W2283525086 hasLocation W22835250861 @default.
- W2283525086 hasOpenAccess W2283525086 @default.
- W2283525086 hasPrimaryLocation W22835250861 @default.
- W2283525086 hasRelatedWork W2000171880 @default.
- W2283525086 hasRelatedWork W2138145596 @default.
- W2283525086 hasRelatedWork W2149893136 @default.
- W2283525086 hasRelatedWork W2163046863 @default.
- W2283525086 hasRelatedWork W2282771152 @default.
- W2283525086 hasRelatedWork W2407044057 @default.
- W2283525086 hasRelatedWork W2804985256 @default.
- W2283525086 hasRelatedWork W2807802647 @default.
- W2283525086 hasRelatedWork W63879797 @default.
- W2283525086 hasRelatedWork W1684679336 @default.
- W2283525086 hasVolume "128" @default.
- W2283525086 isParatext "false" @default.
- W2283525086 isRetracted "false" @default.
- W2283525086 magId "2283525086" @default.
- W2283525086 workType "article" @default.