FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2283759521> ?p ?o ?g. }

• W2283759521 endingPage "136" @default.
• W2283759521 startingPage "127" @default.
• W2283759521 abstract "Radiogenomics designates a scientific field that addresses possible associations between genetic germline alterations and normal tissue toxicity after radiotherapy. The ultimate aim of this research is to establish a gene-based predictive test for normal tissue radiosensitivity. During the last 5 years, substantial progress has been achieved in this field. Several compelling associations for SNPs have been demonstrated in large candidate gene studies as well as genome wide association studies. These findings shed new light on radiobiology and expand our understanding of the processes that lead to side effects after radiotherapy. Despite this, certain fundamental challenges still relate to genomic approaches. Based on the latest insights into complex trait genetics and molecular genetics, we provide an analysis of these challenges and propose putative strategies to further advance the field. These strategies include ‘big data approaches’ and collaborative research within international consortia. Furthermore, research that combines the study of radiation-induced gene expression and genome-wide SNP genotype may discover genetic alterations that regulate the biological response to ionizing radiation. Thus, such integrative approaches may lead to genetic alterations that affect risk of normal tissue toxicity." @default.
• W2283759521 created "2016-06-24" @default.
• W2283759521 creator A5012289366 @default.
• W2283759521 creator A5071977658 @default.
• W2283759521 creator A5080461637 @default.
• W2283759521 creator A5086242617 @default.
• W2283759521 date "2016-11-01" @default.
• W2283759521 modified "2023-10-01" @default.
• W2283759521 title "Radiogenomics – current status, challenges and future directions" @default.
• W2283759521 cites W1561770654 @default.
• W2283759521 cites W1773700395 @default.
• W2283759521 cites W1976548024 @default.
• W2283759521 cites W1978150238 @default.
• W2283759521 cites W1982087764 @default.
• W2283759521 cites W1992891812 @default.
• W2283759521 cites W1993616000 @default.
• W2283759521 cites W1997747933 @default.
• W2283759521 cites W2001280003 @default.
• W2283759521 cites W2002894562 @default.
• W2283759521 cites W2006988918 @default.
• W2283759521 cites W2008966333 @default.
• W2283759521 cites W2012272518 @default.
• W2283759521 cites W2014610710 @default.
• W2283759521 cites W2014709251 @default.
• W2283759521 cites W2021061760 @default.
• W2283759521 cites W2023162983 @default.
• W2283759521 cites W2033102397 @default.
• W2283759521 cites W2034096305 @default.
• W2283759521 cites W2034617404 @default.
• W2283759521 cites W2039846010 @default.
• W2283759521 cites W2041543450 @default.
• W2283759521 cites W2041968228 @default.
• W2283759521 cites W2052785617 @default.
• W2283759521 cites W2056601553 @default.
• W2283759521 cites W2057268591 @default.
• W2283759521 cites W2058660872 @default.
• W2283759521 cites W2062018774 @default.
• W2283759521 cites W2067551453 @default.
• W2283759521 cites W2071217207 @default.
• W2283759521 cites W2072729503 @default.
• W2283759521 cites W2079722579 @default.
• W2283759521 cites W2088754604 @default.
• W2283759521 cites W2090512524 @default.
• W2283759521 cites W2095297132 @default.
• W2283759521 cites W2109317905 @default.
• W2283759521 cites W2109878456 @default.
• W2283759521 cites W2116372696 @default.
• W2283759521 cites W2116868464 @default.
• W2283759521 cites W2122388560 @default.
• W2283759521 cites W2139852278 @default.
• W2283759521 cites W2154975266 @default.
• W2283759521 cites W2158907650 @default.
• W2283759521 cites W2162824911 @default.
• W2283759521 cites W2166283970 @default.
• W2283759521 cites W2171838276 @default.
• W2283759521 cites W2187181884 @default.
• W2283759521 cites W2318817501 @default.
• W2283759521 cites W2341885506 @default.
• W2283759521 cites W774567926 @default.
• W2283759521 doi "https://doi.org/10.1016/j.canlet.2016.01.035" @default.
• W2283759521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26828014" @default.
• W2283759521 hasPublicationYear "2016" @default.
• W2283759521 type Work @default.
• W2283759521 sameAs 2283759521 @default.
• W2283759521 citedByCount "62" @default.
• W2283759521 countsByYear W22837595212016 @default.
• W2283759521 countsByYear W22837595212017 @default.
• W2283759521 countsByYear W22837595212018 @default.
• W2283759521 countsByYear W22837595212019 @default.
• W2283759521 countsByYear W22837595212020 @default.
• W2283759521 countsByYear W22837595212021 @default.
• W2283759521 countsByYear W22837595212022 @default.
• W2283759521 countsByYear W22837595212023 @default.
• W2283759521 crossrefType "journal-article" @default.
• W2283759521 hasAuthorship W2283759521A5012289366 @default.
• W2283759521 hasAuthorship W2283759521A5071977658 @default.
• W2283759521 hasAuthorship W2283759521A5080461637 @default.
• W2283759521 hasAuthorship W2283759521A5086242617 @default.
• W2283759521 hasConcept C104317684 @default.
• W2283759521 hasConcept C106208931 @default.
• W2283759521 hasConcept C126838900 @default.
• W2283759521 hasConcept C135763542 @default.
• W2283759521 hasConcept C139275648 @default.
• W2283759521 hasConcept C153209595 @default.
• W2283759521 hasConcept C163500349 @default.
• W2283759521 hasConcept C2778559731 @default.
• W2283759521 hasConcept C47042493 @default.
• W2283759521 hasConcept C54355233 @default.
• W2283759521 hasConcept C60644358 @default.
• W2283759521 hasConcept C70721500 @default.
• W2283759521 hasConcept C71924100 @default.
• W2283759521 hasConcept C86803240 @default.
• W2283759521 hasConceptScore W2283759521C104317684 @default.
• W2283759521 hasConceptScore W2283759521C106208931 @default.
• W2283759521 hasConceptScore W2283759521C126838900 @default.
• W2283759521 hasConceptScore W2283759521C135763542 @default.
• W2283759521 hasConceptScore W2283759521C139275648 @default.
• W2283759521 hasConceptScore W2283759521C153209595 @default.

• next