Matches in SemOpenAlex for { <https://semopenalex.org/work/W2283762488> ?p ?o ?g. }
- W2283762488 endingPage "63" @default.
- W2283762488 startingPage "56" @default.
- W2283762488 abstract "Intestinal epithelial secretion is coordinated by the submucosal plexus (SMP). Chemical mediators from SMP regulate the immunobiological response and direct actions against infectious agents. Toxoplasma gondii is a worldwide parasite that causes toxoplasmosis. This study aimed to determine the effects of chronic infection with T. gondii on the morphometry of the mucosa and the submucosal enteric neurons in the proximal colon of rats. Male adult rats were distributed into a control group (n = 10) and an infected group (n = 10). Infected rats received orally 500 oocysts of T. gondii (ME-49). After 36 days, the rats were euthanized and samples of the proximal colon were processed for histology to evaluate mucosal thickness in sections. Whole mounts were stained with methylene blue and subjected to immunohistochemistry to detect vasoactive intestinal polypeptide. The total number of submucosal neurons decreased by 16.20%. Vasoactive intestinal polypeptide-immunoreactive neurons increased by 26.95%. Intraepithelial lymphocytes increased by 62.86% and sulfomucin-producing goblet cells decreased by 22.87%. Crypt depth was greater by 43.02%. It was concluded that chronic infection with T. gondii induced death and hypertrophy in the remaining submucosal enteric neurons and damage to the colonic mucosa of rats." @default.
- W2283762488 created "2016-06-24" @default.
- W2283762488 creator A5017926460 @default.
- W2283762488 creator A5022801137 @default.
- W2283762488 creator A5047670820 @default.
- W2283762488 creator A5050424318 @default.
- W2283762488 creator A5057220773 @default.
- W2283762488 creator A5064269413 @default.
- W2283762488 creator A5066092769 @default.
- W2283762488 creator A5086685439 @default.
- W2283762488 date "2016-05-01" @default.
- W2283762488 modified "2023-10-06" @default.
- W2283762488 title "Chronic infection with Toxoplasma gondii induces death of submucosal enteric neurons and damage in the colonic mucosa of rats" @default.
- W2283762488 cites W1516887940 @default.
- W2283762488 cites W1662893264 @default.
- W2283762488 cites W1964502660 @default.
- W2283762488 cites W1979466628 @default.
- W2283762488 cites W1986936967 @default.
- W2283762488 cites W1989975502 @default.
- W2283762488 cites W1998397250 @default.
- W2283762488 cites W2000903574 @default.
- W2283762488 cites W2006479087 @default.
- W2283762488 cites W2015121095 @default.
- W2283762488 cites W2015659662 @default.
- W2283762488 cites W2026971413 @default.
- W2283762488 cites W2027435977 @default.
- W2283762488 cites W2028257315 @default.
- W2283762488 cites W2039255033 @default.
- W2283762488 cites W2046716449 @default.
- W2283762488 cites W2055769360 @default.
- W2283762488 cites W2060180980 @default.
- W2283762488 cites W2067856123 @default.
- W2283762488 cites W2072773040 @default.
- W2283762488 cites W2074826445 @default.
- W2283762488 cites W2080410042 @default.
- W2283762488 cites W2080588636 @default.
- W2283762488 cites W2080999285 @default.
- W2283762488 cites W2081961338 @default.
- W2283762488 cites W2084739683 @default.
- W2283762488 cites W2090303039 @default.
- W2283762488 cites W2091097124 @default.
- W2283762488 cites W2100787708 @default.
- W2283762488 cites W2108129929 @default.
- W2283762488 cites W2120950548 @default.
- W2283762488 cites W2127643922 @default.
- W2283762488 cites W2129342724 @default.
- W2283762488 cites W2129785704 @default.
- W2283762488 cites W2133065046 @default.
- W2283762488 cites W2143423474 @default.
- W2283762488 cites W2148908418 @default.
- W2283762488 cites W2151165347 @default.
- W2283762488 cites W2152668112 @default.
- W2283762488 cites W2154926052 @default.
- W2283762488 cites W2156154614 @default.
- W2283762488 cites W273258560 @default.
- W2283762488 cites W4292408069 @default.
- W2283762488 cites W592913265 @default.
- W2283762488 doi "https://doi.org/10.1016/j.exppara.2016.02.009" @default.
- W2283762488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26902605" @default.
- W2283762488 hasPublicationYear "2016" @default.
- W2283762488 type Work @default.
- W2283762488 sameAs 2283762488 @default.
- W2283762488 citedByCount "18" @default.
- W2283762488 countsByYear W22837624882017 @default.
- W2283762488 countsByYear W22837624882018 @default.
- W2283762488 countsByYear W22837624882019 @default.
- W2283762488 countsByYear W22837624882020 @default.
- W2283762488 countsByYear W22837624882021 @default.
- W2283762488 countsByYear W22837624882023 @default.
- W2283762488 crossrefType "journal-article" @default.
- W2283762488 hasAuthorship W2283762488A5017926460 @default.
- W2283762488 hasAuthorship W2283762488A5022801137 @default.
- W2283762488 hasAuthorship W2283762488A5047670820 @default.
- W2283762488 hasAuthorship W2283762488A5050424318 @default.
- W2283762488 hasAuthorship W2283762488A5057220773 @default.
- W2283762488 hasAuthorship W2283762488A5064269413 @default.
- W2283762488 hasAuthorship W2283762488A5066092769 @default.
- W2283762488 hasAuthorship W2283762488A5086685439 @default.
- W2283762488 hasConcept C118303440 @default.
- W2283762488 hasConcept C126322002 @default.
- W2283762488 hasConcept C134018914 @default.
- W2283762488 hasConcept C142724271 @default.
- W2283762488 hasConcept C152605822 @default.
- W2283762488 hasConcept C159654299 @default.
- W2283762488 hasConcept C170493617 @default.
- W2283762488 hasConcept C203014093 @default.
- W2283762488 hasConcept C204232928 @default.
- W2283762488 hasConcept C2776907353 @default.
- W2283762488 hasConcept C2777310793 @default.
- W2283762488 hasConcept C2777439022 @default.
- W2283762488 hasConcept C2778128430 @default.
- W2283762488 hasConcept C3019368612 @default.
- W2283762488 hasConcept C529295009 @default.
- W2283762488 hasConcept C54355233 @default.
- W2283762488 hasConcept C55493867 @default.
- W2283762488 hasConcept C71924100 @default.
- W2283762488 hasConcept C8330315 @default.
- W2283762488 hasConcept C86803240 @default.