Matches in SemOpenAlex for { <https://semopenalex.org/work/W2284067672> ?p ?o ?g. }
Showing items 1 to 63 of
63
with 100 items per page.
- W2284067672 endingPage "161S" @default.
- W2284067672 startingPage "154S" @default.
- W2284067672 abstract "Recently, attention has focused on the effects of calcium antagonists on renal function. When administered in vitro to the isolated perfused kidney, calcium antagonists exhibit consistent actions, permitting characterization of their renal effects. Calcium antagonists do not affect the vasodilated isolated perfused kidney, but they do dramatically alter the response of the kidney to vasoconstrictor agents. In the presence of norepinephrine, calcium antagonists markedly augment the glomerular filtration rate, but produce only a modest improvement in renal perfusion. By use of the postischemic, hydronephrotic rat kidney model, which permits direct visualization of afferent and efferent arterioles, it can be demonstrated that the abovementioned preferential augmentation of glomerular filtration rate may be attributable to a selective vasodilation of preglomerular vessels. Although the clinical implications of such observations are not yet clear, preliminary studies in experimental animal models indicate that calcium antagonists might exert salutary effects on renal function in clinical settings characterized by impaired renal hemodynamics. There is a need to carry out prospective studies to determine the benefits of calcium antagonists in ameliorating the development of renal dysfunction in patients at risk of acute renal insufficiency. Am J Hypertens 1989;2:154S–161S" @default.
- W2284067672 created "2016-06-24" @default.
- W2284067672 creator A5035092157 @default.
- W2284067672 creator A5050917741 @default.
- W2284067672 date "1989-06-01" @default.
- W2284067672 modified "2023-10-15" @default.
- W2284067672 title "Calcium Antagonists and the Kidney" @default.
- W2284067672 doi "https://doi.org/10.1093/ajh/2.6.154s" @default.
- W2284067672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2665786" @default.
- W2284067672 hasPublicationYear "1989" @default.
- W2284067672 type Work @default.
- W2284067672 sameAs 2284067672 @default.
- W2284067672 citedByCount "34" @default.
- W2284067672 countsByYear W22840676722015 @default.
- W2284067672 crossrefType "journal-article" @default.
- W2284067672 hasAuthorship W2284067672A5035092157 @default.
- W2284067672 hasAuthorship W2284067672A5050917741 @default.
- W2284067672 hasConcept C126322002 @default.
- W2284067672 hasConcept C126894567 @default.
- W2284067672 hasConcept C134018914 @default.
- W2284067672 hasConcept C142225936 @default.
- W2284067672 hasConcept C159641895 @default.
- W2284067672 hasConcept C198710026 @default.
- W2284067672 hasConcept C2780091579 @default.
- W2284067672 hasConcept C2780636983 @default.
- W2284067672 hasConcept C2781073237 @default.
- W2284067672 hasConcept C519063684 @default.
- W2284067672 hasConcept C71924100 @default.
- W2284067672 hasConcept C84393581 @default.
- W2284067672 hasConceptScore W2284067672C126322002 @default.
- W2284067672 hasConceptScore W2284067672C126894567 @default.
- W2284067672 hasConceptScore W2284067672C134018914 @default.
- W2284067672 hasConceptScore W2284067672C142225936 @default.
- W2284067672 hasConceptScore W2284067672C159641895 @default.
- W2284067672 hasConceptScore W2284067672C198710026 @default.
- W2284067672 hasConceptScore W2284067672C2780091579 @default.
- W2284067672 hasConceptScore W2284067672C2780636983 @default.
- W2284067672 hasConceptScore W2284067672C2781073237 @default.
- W2284067672 hasConceptScore W2284067672C519063684 @default.
- W2284067672 hasConceptScore W2284067672C71924100 @default.
- W2284067672 hasConceptScore W2284067672C84393581 @default.
- W2284067672 hasIssue "6_Pt_2" @default.
- W2284067672 hasLocation W22840676721 @default.
- W2284067672 hasLocation W22840676722 @default.
- W2284067672 hasOpenAccess W2284067672 @default.
- W2284067672 hasPrimaryLocation W22840676721 @default.
- W2284067672 hasRelatedWork W1952674006 @default.
- W2284067672 hasRelatedWork W1969483979 @default.
- W2284067672 hasRelatedWork W1975785459 @default.
- W2284067672 hasRelatedWork W2027501734 @default.
- W2284067672 hasRelatedWork W2088803614 @default.
- W2284067672 hasRelatedWork W2113212748 @default.
- W2284067672 hasRelatedWork W2132431277 @default.
- W2284067672 hasRelatedWork W2401142930 @default.
- W2284067672 hasRelatedWork W4206496899 @default.
- W2284067672 hasRelatedWork W2090172537 @default.
- W2284067672 hasVolume "2" @default.
- W2284067672 isParatext "false" @default.
- W2284067672 isRetracted "false" @default.
- W2284067672 magId "2284067672" @default.
- W2284067672 workType "article" @default.