FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2284075717> ?p ?o ?g. }

• W2284075717 endingPage "e19532" @default.
• W2284075717 startingPage "e19532" @default.
• W2284075717 abstract "e19532 Background: Number of elderly people is growing and with them the possibility to develop cancer. Specific cares and particularly chemotherapy must allow to maintain their quality of life. Methods: From 2003 to 2006, cohort of 364 patients older than 70 years with cancer was evaluated by oncologist and geriatrician before chemotherapy in public and private hospitals in south-west of France. Quality of life of patients was appreciated by QLQ-C30 completion. Standard geriatric evaluation occurred and oncologic endpoints were collected . Global quality of life, functions and symptoms items were calculated according to Aaronson (JNCI 1993) using EORTC SAS Program provided. Results: Median age was 77.5 years [range 70-99.4] and sex ratio was 214/150 (M/F). Most of patients had metastatic status 65.6% (n = 231) among several cancer location. Creatinine clearance was <50ml/min in 42% (n = 153) and 29.9% presented one comorbidity grade 3-4 and 8.3% at least 2 comorbidities. Global quality of life was not related to age, cancer location and metastatic status. Global quality of life was associated with sex (p = 0.014), toxicities during treatment (0.014), weight loss (p<10-3), performance status (p<10-3) and death within 6 months of treatment beginning. Except for comorbidities, all elements from geriatric standard evaluation were linked significantly to global quality of life. All functions (physical, role, cognitive, emotional and social) were stronghtly associated with weight loss (<5%, 5 to 10%, >10%) (p<10-3) and MNA (≤23.5 vs >23.5) (p<10-3) as well as performance status (0-1 vs. >1) (p<10-3) and IADL (≤7 vs. >7) omitting emotion (p = 10-3). Most of symptoms were related to weight loss and MNA (excepted financial impact and dyspnea) (p = 10-3) and in majority (fatigue, pain, appetite loss) they were linked to poor performance status (p<10-3) and low IADL score (p = 10-3). Conclusions: Poor Global quality of life was correlated to poor scores of standard geriatric evaluation and early death. Altered functions and presence of symptoms were related to malnutrition status (weight loss, poor MNA) and loss of autonomy (poor performance status and low IADL). No significant financial relationships to disclose." @default.
• W2284075717 created "2016-06-24" @default.
• W2284075717 creator A5010120065 @default.
• W2284075717 creator A5018037138 @default.
• W2284075717 creator A5019074662 @default.
• W2284075717 creator A5029447582 @default.
• W2284075717 creator A5039391833 @default.
• W2284075717 creator A5044397434 @default.
• W2284075717 creator A5088177929 @default.
• W2284075717 date "2010-05-20" @default.
• W2284075717 modified "2023-10-18" @default.
• W2284075717 title "Correlation of quality of life with nutritional status and autonomy in elderly cancer patients according to standard geriatric evaluation." @default.
• W2284075717 doi "https://doi.org/10.1200/jco.2010.28.15_suppl.e19532" @default.
• W2284075717 hasPublicationYear "2010" @default.
• W2284075717 type Work @default.
• W2284075717 sameAs 2284075717 @default.
• W2284075717 citedByCount "0" @default.
• W2284075717 crossrefType "journal-article" @default.
• W2284075717 hasAuthorship W2284075717A5010120065 @default.
• W2284075717 hasAuthorship W2284075717A5018037138 @default.
• W2284075717 hasAuthorship W2284075717A5019074662 @default.
• W2284075717 hasAuthorship W2284075717A5029447582 @default.
• W2284075717 hasAuthorship W2284075717A5039391833 @default.
• W2284075717 hasAuthorship W2284075717A5044397434 @default.
• W2284075717 hasAuthorship W2284075717A5088177929 @default.
• W2284075717 hasConcept C121608353 @default.
• W2284075717 hasConcept C126322002 @default.
• W2284075717 hasConcept C159110408 @default.
• W2284075717 hasConcept C2776907518 @default.
• W2284075717 hasConcept C2777319248 @default.
• W2284075717 hasConcept C2779159551 @default.
• W2284075717 hasConcept C2779951463 @default.
• W2284075717 hasConcept C511355011 @default.
• W2284075717 hasConcept C544821477 @default.
• W2284075717 hasConcept C71924100 @default.
• W2284075717 hasConcept C72563966 @default.
• W2284075717 hasConcept C74909509 @default.
• W2284075717 hasConceptScore W2284075717C121608353 @default.
• W2284075717 hasConceptScore W2284075717C126322002 @default.
• W2284075717 hasConceptScore W2284075717C159110408 @default.
• W2284075717 hasConceptScore W2284075717C2776907518 @default.
• W2284075717 hasConceptScore W2284075717C2777319248 @default.
• W2284075717 hasConceptScore W2284075717C2779159551 @default.
• W2284075717 hasConceptScore W2284075717C2779951463 @default.
• W2284075717 hasConceptScore W2284075717C511355011 @default.
• W2284075717 hasConceptScore W2284075717C544821477 @default.
• W2284075717 hasConceptScore W2284075717C71924100 @default.
• W2284075717 hasConceptScore W2284075717C72563966 @default.
• W2284075717 hasConceptScore W2284075717C74909509 @default.
• W2284075717 hasIssue "15_suppl" @default.
• W2284075717 hasLocation W22840757171 @default.
• W2284075717 hasOpenAccess W2284075717 @default.
• W2284075717 hasPrimaryLocation W22840757171 @default.
• W2284075717 hasRelatedWork W1971525631 @default.
• W2284075717 hasRelatedWork W2036532871 @default.
• W2284075717 hasRelatedWork W2081920128 @default.
• W2284075717 hasRelatedWork W2087176428 @default.
• W2284075717 hasRelatedWork W2099473657 @default.
• W2284075717 hasRelatedWork W2284075717 @default.
• W2284075717 hasRelatedWork W2603773853 @default.
• W2284075717 hasRelatedWork W2981576095 @default.
• W2284075717 hasRelatedWork W3096529196 @default.
• W2284075717 hasRelatedWork W3127971205 @default.
• W2284075717 hasVolume "28" @default.
• W2284075717 isParatext "false" @default.
• W2284075717 isRetracted "false" @default.
• W2284075717 magId "2284075717" @default.
• W2284075717 workType "article" @default.