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- W2284370343 abstract "The circadian system regulates biological rhythmicity in the human body. The role of the circadian system in neurological disorders is a theme that is attracting an increasing amount of interest from the scientific community. This has arisen, in part, from emerging evidence that disorders such as Parkinson's disease (PD) are multifactorial with many features exhibiting diurnal fluctuations, thereby suggestive of circadian involvement. Although the importance of fluctuating motor and nonmotor manifestations in PD have been well acknowledged, the role of the circadian system has received little attention until recently. It is proposed that intervening with circadian function provides a novel research avenue down which new strategies for improving symptomatic treatment and slowing of the progressive degenerative process can be approached to lessen the burden of PD. In this article we review the literature describing existing circadian research in PD and its experimental models." @default.
- W2284370343 created "2016-06-24" @default.
- W2284370343 creator A5083282772 @default.
- W2284370343 creator A5088770561 @default.
- W2284370343 date "2016-01-30" @default.
- W2284370343 modified "2023-10-14" @default.
- W2284370343 title "Circadian system - A novel diagnostic and therapeutic target in Parkinson's disease?" @default.
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- W2284370343 doi "https://doi.org/10.1002/mds.26509" @default.
- W2284370343 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4783245" @default.
- W2284370343 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26826022" @default.
- W2284370343 hasPublicationYear "2016" @default.
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