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- W2284476571 abstract "The efficacy of medroxyprogesterone acetate (MPA) in the treatment of recurrent or metastatic endometrial carcinoma was studied in 28 women. 19 of the 28 patients had pretreatment vaginal smears characterized by estrogenic stimulation and a high Karyopyknotic Index. Exclusive oral and intramuscular MPA treatment resulted in the disappearance of superficial and intermediate cells in 13 patients. A completely atrophic vaginal smear was observed by Week 4 of treatment in these patients. The tumor completely regressed in 8 patients 55 years of age or older who showed atrophic smears in response to MPA. MPA therapy had little effect on the remaining patients. The therapy had virtually no effect on patients who had an initially atrophic vaginal smear." @default.
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- W2284476571 date "1970-05-01" @default.
- W2284476571 modified "2023-09-23" @default.
- W2284476571 title "Cytologic evaluation of exclusive medroxyprogesterone acetate treatment for vaginal recurrence of endometrial adenocarcinoma." @default.
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