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- W2284612922 abstract "Sickle cell disease (SCD) is the most prevalent hemoglobinopathy in the USA. It has been reported that children with SCD have an increased risk for sleep problems including sleep-disordered breathing (SDB) compared to the general pediatric population. These children are also at an increased risk for adenotonsillar hypertrophy due to secondary hyperplasia of the lymphoid tissues following splenic infarction and extramedullary hematopoiesis. They are, therefore, more likely to develop upper airway obstruction. Both daytime and nocturnal hypoxemias are common in children with SCD; however, the accuracy of pulse oximetry in measuring oxyhemoglobin saturation has been questioned by several investigators. In this chapter, we attempt to review the prevalence of various sleep problems including SDB in children with SCD and discuss the link between SCD and hypoxemia, SDB, vaso-occlusive crises, stroke, and pulmonary hypertension. We review common sleep problems and their clinical presentation in children with SCD and outline their evaluation and treatment strategies." @default.
- W2284612922 created "2016-06-24" @default.
- W2284612922 creator A5047657772 @default.
- W2284612922 creator A5052755790 @default.
- W2284612922 creator A5064630672 @default.
- W2284612922 date "2012-01-01" @default.
- W2284612922 modified "2023-09-23" @default.
- W2284612922 title "Sleep Problems in Children with Sickle Cell Disease" @default.
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- W2284612922 doi "https://doi.org/10.1007/978-1-60761-725-9_24" @default.
- W2284612922 hasPublicationYear "2012" @default.
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