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- W2285139964 abstract "The reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is lengthy and inefficient. The development of a reprogramming system that allows rapid and synchronous reprogramming to pluripotency is imperative for understanding the mechanism of iPSC formation and for future therapeutic applications. We have recently reported that a short expression in mouse primary B cells of the transcription factor C/EBPα before the induction of pluripotency factors increases the iPSC reprogramming efficiency >100-fold, involving 95% of the cells within a week. Here we present a dataset containing the time course of gene expression during this process as determined by microarray and RNA-seq techniques." @default.
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- W2285139964 date "2014-05-27" @default.
- W2285139964 modified "2023-10-16" @default.
- W2285139964 title "Time-resolved gene expression profiling during reprogramming of C/EBPα-pulsed B cells into iPS cells" @default.
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- W2285139964 doi "https://doi.org/10.1038/sdata.2014.8" @default.
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