Matches in SemOpenAlex for { <https://semopenalex.org/work/W2285208216> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2285208216 endingPage "34" @default.
- W2285208216 startingPage "31" @default.
- W2285208216 abstract "Coeliac disease is an autoimmune enteropathy triggered by the ingestion of gluten-containing cereals, such as wheat, rye and barley. It is estimated to occur in one per cent of people of European ancestry, and in 0.3% of black Africans. Coeliac disease has a strong genetic component as nearly all patients with the disease share the same genetic predisposition in the form of the presence of either the human leukocyte antigen (HLA)-DQ2 or HLA-DQ8 alleles. The spectrum of symptoms ranges from asymptomatic to chronic diarrhoea, flatulence, abdominal pain and weight loss. Although serological testing for tissue transglutaminase antibodies is both sensitive and specific for the disease, and reflects disease activity, small bowel biopsy is considered to be the standard when diagnosing the disease. The therapy for coeliac disease is a gluten-free diet, which may be difficult and expensive to follow. Nonadherence to a gluten-free diet is the main cause of persistent or recurrent symptoms. Coeliac disease increases the risk of malignancies, such as small bowel adenocarcinoma and enteropathy-associated T-cell lymphoma; pathologies which should be excluded in patients who are compliant with the diet but who are either persistently symptomatic or have a reoccurrence of symptoms. Because coeliac disease is an important cause of common gastrointestinal symptoms and may have significant long-term complications if left untreated, it is paramount that the family practitioner should consider it in the differential diagnosis of patients who present with suspected symptoms. The perception of coeliac disease has changed in recent years from an uncommon enteropathy to a common multisystem disease with a strong genetic predisposition." @default.
- W2285208216 created "2016-06-24" @default.
- W2285208216 creator A5021809368 @default.
- W2285208216 date "2014-01-01" @default.
- W2285208216 modified "2023-09-28" @default.
- W2285208216 title "Coeliac disease : CPD article" @default.
- W2285208216 hasPublicationYear "2014" @default.
- W2285208216 type Work @default.
- W2285208216 sameAs 2285208216 @default.
- W2285208216 citedByCount "0" @default.
- W2285208216 crossrefType "journal-article" @default.
- W2285208216 hasAuthorship W2285208216A5021809368 @default.
- W2285208216 hasConcept C126322002 @default.
- W2285208216 hasConcept C142724271 @default.
- W2285208216 hasConcept C147483822 @default.
- W2285208216 hasConcept C178498320 @default.
- W2285208216 hasConcept C181199279 @default.
- W2285208216 hasConcept C185592680 @default.
- W2285208216 hasConcept C188280979 @default.
- W2285208216 hasConcept C203014093 @default.
- W2285208216 hasConcept C2776336767 @default.
- W2285208216 hasConcept C2777910003 @default.
- W2285208216 hasConcept C2778426112 @default.
- W2285208216 hasConcept C2779134260 @default.
- W2285208216 hasConcept C2780349322 @default.
- W2285208216 hasConcept C55493867 @default.
- W2285208216 hasConcept C67636389 @default.
- W2285208216 hasConcept C71924100 @default.
- W2285208216 hasConcept C90924648 @default.
- W2285208216 hasConceptScore W2285208216C126322002 @default.
- W2285208216 hasConceptScore W2285208216C142724271 @default.
- W2285208216 hasConceptScore W2285208216C147483822 @default.
- W2285208216 hasConceptScore W2285208216C178498320 @default.
- W2285208216 hasConceptScore W2285208216C181199279 @default.
- W2285208216 hasConceptScore W2285208216C185592680 @default.
- W2285208216 hasConceptScore W2285208216C188280979 @default.
- W2285208216 hasConceptScore W2285208216C203014093 @default.
- W2285208216 hasConceptScore W2285208216C2776336767 @default.
- W2285208216 hasConceptScore W2285208216C2777910003 @default.
- W2285208216 hasConceptScore W2285208216C2778426112 @default.
- W2285208216 hasConceptScore W2285208216C2779134260 @default.
- W2285208216 hasConceptScore W2285208216C2780349322 @default.
- W2285208216 hasConceptScore W2285208216C55493867 @default.
- W2285208216 hasConceptScore W2285208216C67636389 @default.
- W2285208216 hasConceptScore W2285208216C71924100 @default.
- W2285208216 hasConceptScore W2285208216C90924648 @default.
- W2285208216 hasIssue "1" @default.
- W2285208216 hasLocation W22852082161 @default.
- W2285208216 hasOpenAccess W2285208216 @default.
- W2285208216 hasPrimaryLocation W22852082161 @default.
- W2285208216 hasRelatedWork W128705992 @default.
- W2285208216 hasRelatedWork W1993638096 @default.
- W2285208216 hasRelatedWork W1995774180 @default.
- W2285208216 hasRelatedWork W2004807140 @default.
- W2285208216 hasRelatedWork W2005595667 @default.
- W2285208216 hasRelatedWork W2020479025 @default.
- W2285208216 hasRelatedWork W2040108457 @default.
- W2285208216 hasRelatedWork W2058904047 @default.
- W2285208216 hasRelatedWork W2058989566 @default.
- W2285208216 hasRelatedWork W2111166514 @default.
- W2285208216 hasRelatedWork W2128532861 @default.
- W2285208216 hasRelatedWork W2141850533 @default.
- W2285208216 hasRelatedWork W2150794285 @default.
- W2285208216 hasRelatedWork W2417383655 @default.
- W2285208216 hasRelatedWork W2419500215 @default.
- W2285208216 hasRelatedWork W2749562815 @default.
- W2285208216 hasRelatedWork W288549672 @default.
- W2285208216 hasRelatedWork W3023551049 @default.
- W2285208216 hasRelatedWork W2510654654 @default.
- W2285208216 hasRelatedWork W3140092413 @default.
- W2285208216 hasVolume "56" @default.
- W2285208216 isParatext "false" @default.
- W2285208216 isRetracted "false" @default.
- W2285208216 magId "2285208216" @default.
- W2285208216 workType "article" @default.