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• W2285341745 abstract "This thesis demonstrates the relationship between depression symptomatology and white matter microstructure.Chapter 1 provides a systematic literature overview on white matter microstructurealterations of the reward system in depression. Findings suggest that localization and extent of white matter microstructure alterations in depression is highlydependent on the state (depression vs. remission) and the clinical subtype.Using a novel tractography algorithm, Chapter 2 provides a comprehensiveinstruction on how to delineate the two different branches of the MFB (supero-lateralmedial forebrain bundle (slMFB) and infero-medial medial forebrain bundle(imMFB)), the main pathway of the reward system. An association betweenfractional anisotropy (FA), a diffusion tensor imaging (DTI)-based measure that issupposed to reflect white matter microstructure and hedonic tone, the capacity to derive pleasure from rewarding experiences is identified across a group of remitted depressed (RD) and never depressed (ND) young women.Chapter 3 uses a longitudinal design to investigate white matter microstructuralchanges of different pathways of the reward system from depression to remission. A distinct pattern of changes that depends on both the tract and the age is identified.Chapter 4 investigates the structural correlates of physical activity (PA). PA is reduced in depression and its benefit for depression symptomatology is well known.Using an MRI-sequence that has been shown to be specific to myelination we identify a positive correlation between PA and myelination of the right parahippocampal cingulum (PHC).This thesis contributes to the identification of structure-function associations related to the reward system in both patients with major depressive disorder (MDD) and healthy controls (HC). Results call for a careful stratification of clinically meaningfulhomogeneous subgroups if investigating participants with depression. Further the benefit of novel imaging methods for reconstruction of specific pathways and for aneurobiologically meaningful interpretation of the data is clearly shown." @default.
• W2285341745 created "2016-06-24" @default.
• W2285341745 creator A5062908749 @default.
• W2285341745 date "2015-01-01" @default.
• W2285341745 modified "2023-09-27" @default.
• W2285341745 title "Characterizing white matter microstructure of the reward system in depression" @default.
• W2285341745 cites W1499836032 @default.
• W2285341745 cites W1584789181 @default.
• W2285341745 cites W1733837299 @default.
• W2285341745 cites W1849553904 @default.
• W2285341745 cites W1959902108 @default.
• W2285341745 cites W1963521908 @default.
• W2285341745 cites W1964065874 @default.
• W2285341745 cites W1965348011 @default.
• W2285341745 cites W1965400726 @default.
• W2285341745 cites W1967881653 @default.
• W2285341745 cites W1968837585 @default.
• W2285341745 cites W1973127790 @default.
• W2285341745 cites W1974695557 @default.
• W2285341745 cites W1983559498 @default.
• W2285341745 cites W1983961948 @default.
• W2285341745 cites W1984142725 @default.
• W2285341745 cites W1987493933 @default.
• W2285341745 cites W1987494247 @default.
• W2285341745 cites W1993524834 @default.
• W2285341745 cites W1994204698 @default.
• W2285341745 cites W1994414964 @default.
• W2285341745 cites W1994972002 @default.
• W2285341745 cites W1995188451 @default.
• W2285341745 cites W1996458768 @default.
• W2285341745 cites W1996878671 @default.
• W2285341745 cites W1997245512 @default.
• W2285341745 cites W1997971699 @default.
• W2285341745 cites W1999919402 @default.
• W2285341745 cites W2000226539 @default.
• W2285341745 cites W2001367656 @default.
• W2285341745 cites W2003539800 @default.
• W2285341745 cites W2003892612 @default.
• W2285341745 cites W2004060777 @default.
• W2285341745 cites W2008753452 @default.
• W2285341745 cites W2009742165 @default.
• W2285341745 cites W2011157006 @default.
• W2285341745 cites W2012405016 @default.
• W2285341745 cites W2013150278 @default.
• W2285341745 cites W2013657375 @default.
• W2285341745 cites W2013795356 @default.
• W2285341745 cites W2014210717 @default.
• W2285341745 cites W2014380567 @default.
• W2285341745 cites W2016585607 @default.
• W2285341745 cites W2019070177 @default.
• W2285341745 cites W2019531224 @default.
• W2285341745 cites W2019782389 @default.
• W2285341745 cites W2021551531 @default.
• W2285341745 cites W2022181979 @default.
• W2285341745 cites W2022244667 @default.
• W2285341745 cites W2022530159 @default.
• W2285341745 cites W2022658768 @default.
• W2285341745 cites W2023693164 @default.
• W2285341745 cites W2023966843 @default.
• W2285341745 cites W2024212517 @default.
• W2285341745 cites W2025440394 @default.
• W2285341745 cites W2027102257 @default.
• W2285341745 cites W2028425183 @default.
• W2285341745 cites W2028948352 @default.
• W2285341745 cites W2028980996 @default.
• W2285341745 cites W2029232177 @default.
• W2285341745 cites W2030235290 @default.
• W2285341745 cites W2030246759 @default.
• W2285341745 cites W2031322390 @default.
• W2285341745 cites W2032378574 @default.
• W2285341745 cites W2033835343 @default.
• W2285341745 cites W2034073970 @default.
• W2285341745 cites W2035941098 @default.
• W2285341745 cites W2036559773 @default.
• W2285341745 cites W2036713747 @default.
• W2285341745 cites W2037395744 @default.
• W2285341745 cites W2038492389 @default.
• W2285341745 cites W2038722017 @default.
• W2285341745 cites W2041750706 @default.
• W2285341745 cites W2043319706 @default.
• W2285341745 cites W2045355179 @default.
• W2285341745 cites W2045598508 @default.
• W2285341745 cites W2046140176 @default.
• W2285341745 cites W2047152236 @default.
• W2285341745 cites W2049379747 @default.
• W2285341745 cites W2050886347 @default.
• W2285341745 cites W2052460692 @default.
• W2285341745 cites W2052644075 @default.
• W2285341745 cites W2052658506 @default.
• W2285341745 cites W2053093248 @default.
• W2285341745 cites W2053884965 @default.
• W2285341745 cites W2056999109 @default.
• W2285341745 cites W2058255813 @default.
• W2285341745 cites W2059033731 @default.
• W2285341745 cites W2059151261 @default.
• W2285341745 cites W2061378977 @default.
• W2285341745 cites W2063001897 @default.
• W2285341745 cites W2063233148 @default.
• W2285341745 cites W2064383989 @default.
• W2285341745 cites W2064385228 @default.

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