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- W2285943618 abstract "274 Objectives: FDG uptake in the primary tumors and malignant lymph nodes of NSCLC has been reported to be mediated by glucose transporter type 1 (glut-1). The level of FDG uptake in primary tumors may affect the likelihood of malignant involvement in the loco-regional lymph nodes. Therefore, we investigated the correlation of FDG uptake and glut-1 expression between primary tumors and loco-regional lymph nodes of NSCLC. Methods: One hundred twenty-six NSCLC patients (male:female=103:23, age=65±9.7y) who had underwent curative resections and loco-regional lymph node dissections within 4 weeks after FDG-PET study were enrolled. Maximum standardized uptake values (maxSUV) on PET and glut-1 expression percentages on surgical specimens were measured and compared between primary tumors and FDG uptake positive loco-regional lymph nodes. Results: After excluding the peribronchial lymph nodes directly invaded by primary tumors and the benign lymph nodes with no FDG uptake, 126 primary tumors and 196 loco-regional lymph nodes (52 malignant and 144 benign) were analyzed. Fifty-two malignant lymph nodes were compared with 37 primary tumors. There were significantly high correlations of maxSUV (r=0.6399, p" @default.
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- W2285943618 date "2007-05-01" @default.
- W2285943618 modified "2023-09-28" @default.
- W2285943618 title "Correlation of FDG uptake and glucose transporter type 1 expression between primary tumors and loco-regional lymph nodes in non-small-cell lung cancer" @default.
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