FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2285980177> ?p ?o ?g. }

• W2285980177 endingPage "286" @default.
• W2285980177 startingPage "279" @default.
• W2285980177 abstract "Purpose This work proposes a theoretical framework that enables comparative risk predictions for second cancer incidence after particle beam therapy for different ion species for individual patients, accounting for differences in relative biological effectiveness (RBE) for the competing processes of tumor initiation and cell inactivation. Our working hypothesis was that use of carbon-ion therapy instead of proton therapy would show a difference in the predicted risk of second cancer incidence in the breast for a sample of Hodgkin lymphoma (HL) patients. Methods and Materials We generated biologic treatment plans and calculated relative predicted risks of second cancer in the breast by using two proposed methods: a full model derived from the linear quadratic model and a simpler linear-no-threshold model. Results For our reference calculation, we found the predicted risk of breast cancer incidence for carbon-ion plans-to-proton plan ratio, <Rc/Rp>, to be 0.75 ± 0.07 but not significantly smaller than 1 (P=.180). Conclusions Our findings suggest that second cancer risks are, on average, comparable between proton therapy and carbon-ion therapy. This work proposes a theoretical framework that enables comparative risk predictions for second cancer incidence after particle beam therapy for different ion species for individual patients, accounting for differences in relative biological effectiveness (RBE) for the competing processes of tumor initiation and cell inactivation. Our working hypothesis was that use of carbon-ion therapy instead of proton therapy would show a difference in the predicted risk of second cancer incidence in the breast for a sample of Hodgkin lymphoma (HL) patients. We generated biologic treatment plans and calculated relative predicted risks of second cancer in the breast by using two proposed methods: a full model derived from the linear quadratic model and a simpler linear-no-threshold model. For our reference calculation, we found the predicted risk of breast cancer incidence for carbon-ion plans-to-proton plan ratio, <Rc/Rp>, to be 0.75 ± 0.07 but not significantly smaller than 1 (P=.180). Our findings suggest that second cancer risks are, on average, comparable between proton therapy and carbon-ion therapy." @default.
• W2285980177 created "2016-06-24" @default.
• W2285980177 creator A5001234563 @default.
• W2285980177 creator A5023618347 @default.
• W2285980177 creator A5038361086 @default.
• W2285980177 creator A5040557026 @default.
• W2285980177 creator A5058031856 @default.
• W2285980177 creator A5058950599 @default.
• W2285980177 creator A5088678413 @default.
• W2285980177 date "2016-05-01" @default.
• W2285980177 modified "2023-10-17" @default.
• W2285980177 title "Comparative Risk Predictions of Second Cancers After Carbon-Ion Therapy Versus Proton Therapy" @default.
• W2285980177 cites W1823727300 @default.
• W2285980177 cites W1965391694 @default.
• W2285980177 cites W1969921553 @default.
• W2285980177 cites W1991938051 @default.
• W2285980177 cites W1992656004 @default.
• W2285980177 cites W1995536144 @default.
• W2285980177 cites W2005391728 @default.
• W2285980177 cites W2013297982 @default.
• W2285980177 cites W2017529805 @default.
• W2285980177 cites W2020914501 @default.
• W2285980177 cites W2023640892 @default.
• W2285980177 cites W2023772489 @default.
• W2285980177 cites W2033268878 @default.
• W2285980177 cites W2041344443 @default.
• W2285980177 cites W2041535162 @default.
• W2285980177 cites W2053000325 @default.
• W2285980177 cites W2059496322 @default.
• W2285980177 cites W2060936143 @default.
• W2285980177 cites W2066931933 @default.
• W2285980177 cites W2067746169 @default.
• W2285980177 cites W2086862863 @default.
• W2285980177 cites W2087947417 @default.
• W2285980177 cites W2091705392 @default.
• W2285980177 cites W2095154552 @default.
• W2285980177 cites W2096372837 @default.
• W2285980177 cites W2097512974 @default.
• W2285980177 cites W2097823108 @default.
• W2285980177 cites W2098179714 @default.
• W2285980177 cites W2105473228 @default.
• W2285980177 cites W2105751688 @default.
• W2285980177 cites W2112996675 @default.
• W2285980177 cites W2117181072 @default.
• W2285980177 cites W2117275139 @default.
• W2285980177 cites W2118636519 @default.
• W2285980177 cites W2123584102 @default.
• W2285980177 cites W2129146771 @default.
• W2285980177 cites W2133758798 @default.
• W2285980177 cites W2134766048 @default.
• W2285980177 cites W2143888394 @default.
• W2285980177 cites W2153228211 @default.
• W2285980177 cites W2154060905 @default.
• W2285980177 cites W2160226244 @default.
• W2285980177 cites W2163678892 @default.
• W2285980177 cites W2312340292 @default.
• W2285980177 cites W2314026050 @default.
• W2285980177 cites W2916115472 @default.
• W2285980177 cites W4233437052 @default.
• W2285980177 cites W4254629891 @default.
• W2285980177 doi "https://doi.org/10.1016/j.ijrobp.2016.02.032" @default.
• W2285980177 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4844193" @default.
• W2285980177 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27084647" @default.
• W2285980177 hasPublicationYear "2016" @default.
• W2285980177 type Work @default.
• W2285980177 sameAs 2285980177 @default.
• W2285980177 citedByCount "25" @default.
• W2285980177 countsByYear W22859801772016 @default.
• W2285980177 countsByYear W22859801772017 @default.
• W2285980177 countsByYear W22859801772018 @default.
• W2285980177 countsByYear W22859801772019 @default.
• W2285980177 countsByYear W22859801772020 @default.
• W2285980177 countsByYear W22859801772021 @default.
• W2285980177 countsByYear W22859801772022 @default.
• W2285980177 countsByYear W22859801772023 @default.
• W2285980177 crossrefType "journal-article" @default.
• W2285980177 hasAuthorship W2285980177A5001234563 @default.
• W2285980177 hasAuthorship W2285980177A5023618347 @default.
• W2285980177 hasAuthorship W2285980177A5038361086 @default.
• W2285980177 hasAuthorship W2285980177A5040557026 @default.
• W2285980177 hasAuthorship W2285980177A5058031856 @default.
• W2285980177 hasAuthorship W2285980177A5058950599 @default.
• W2285980177 hasAuthorship W2285980177A5088678413 @default.
• W2285980177 hasBestOaLocation W22859801772 @default.
• W2285980177 hasConcept C111337013 @default.
• W2285980177 hasConcept C11928243 @default.
• W2285980177 hasConcept C120665830 @default.
• W2285980177 hasConcept C121332964 @default.
• W2285980177 hasConcept C121608353 @default.
• W2285980177 hasConcept C126322002 @default.
• W2285980177 hasConcept C143998085 @default.
• W2285980177 hasConcept C185544564 @default.
• W2285980177 hasConcept C2778418280 @default.
• W2285980177 hasConcept C2779244869 @default.
• W2285980177 hasConcept C44249647 @default.
• W2285980177 hasConcept C509974204 @default.
• W2285980177 hasConcept C530470458 @default.
• W2285980177 hasConcept C54516573 @default.

• next