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- W2286042919 startingPage "431" @default.
- W2286042919 abstract "Dietary antioxidants such as phenolic phytochemicals may prevent/improve endothelial function impairment observed in cardiovascular diseases. This study investigates the specific protective effects of a vegetal seasoning obtained from seedless wine pomace against hyperglycaemia-induced oxidative damage and dysfunction in human umbilical vein endothelial cells EA.hy926. Non-cytotoxic doses of the bioactive compounds obtained following in vitro digestion of the seasoning were used as treatments. Digested compounds, especially colonic bacterial metabolites, restored a more balanced redox environment, prevented lipid peroxidation and cell membrane damage, ameliorated protein oxidation, and improved the balance between endothelial reactive oxygen species and nitric oxide production in hyperglycaemic cells. Reduction of angiotensin I-converting enzyme activity and gene modulation of superoxide dismutase, haem oxygenase-1, β-nicotinamide adenine dinucleotide phosphate oxidase-4, and endothelial nitric oxide synthase are proposed as the mechanisms underlying this protection. These results support the potential benefits of functional wine pomace seasonings in vascular complications associated with oxidative stress." @default.
- W2286042919 created "2016-06-24" @default.
- W2286042919 creator A5018118238 @default.
- W2286042919 creator A5019484654 @default.
- W2286042919 creator A5023160373 @default.
- W2286042919 creator A5041421822 @default.
- W2286042919 date "2016-04-01" @default.
- W2286042919 modified "2023-10-18" @default.
- W2286042919 title "Wine pomace seasoning attenuates hyperglycaemia-induced endothelial dysfunction and oxidative damage in endothelial cells" @default.
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- W2286042919 cites W1567614586 @default.
- W2286042919 cites W1914622032 @default.
- W2286042919 cites W1964188122 @default.
- W2286042919 cites W1964606025 @default.
- W2286042919 cites W1965158621 @default.
- W2286042919 cites W1968436241 @default.
- W2286042919 cites W1974850809 @default.
- W2286042919 cites W1980885166 @default.
- W2286042919 cites W1980932234 @default.
- W2286042919 cites W1982577638 @default.
- W2286042919 cites W1983470498 @default.
- W2286042919 cites W1984363621 @default.
- W2286042919 cites W1986473930 @default.
- W2286042919 cites W1989622544 @default.
- W2286042919 cites W1992203795 @default.
- W2286042919 cites W1993795415 @default.
- W2286042919 cites W1996806851 @default.
- W2286042919 cites W1997053426 @default.
- W2286042919 cites W1999033829 @default.
- W2286042919 cites W2003589653 @default.
- W2286042919 cites W2007155435 @default.
- W2286042919 cites W2009913387 @default.
- W2286042919 cites W2010311619 @default.
- W2286042919 cites W2011672756 @default.
- W2286042919 cites W2012479775 @default.
- W2286042919 cites W2014890793 @default.
- W2286042919 cites W2023461657 @default.
- W2286042919 cites W2033936517 @default.
- W2286042919 cites W2035907631 @default.
- W2286042919 cites W2048864529 @default.
- W2286042919 cites W2051356017 @default.
- W2286042919 cites W2053115631 @default.
- W2286042919 cites W2058681728 @default.
- W2286042919 cites W2062041092 @default.
- W2286042919 cites W2063193018 @default.
- W2286042919 cites W2065102239 @default.
- W2286042919 cites W2066523855 @default.
- W2286042919 cites W2068201035 @default.
- W2286042919 cites W2072063791 @default.
- W2286042919 cites W2075553180 @default.
- W2286042919 cites W2076147202 @default.
- W2286042919 cites W2081131607 @default.
- W2286042919 cites W2084727563 @default.
- W2286042919 cites W2086797182 @default.
- W2286042919 cites W2091616621 @default.
- W2286042919 cites W2099682888 @default.
- W2286042919 cites W2100134388 @default.
- W2286042919 cites W2101539980 @default.
- W2286042919 cites W2104862661 @default.
- W2286042919 cites W2105234557 @default.
- W2286042919 cites W2105744925 @default.
- W2286042919 cites W2109168147 @default.
- W2286042919 cites W2111680912 @default.
- W2286042919 cites W2113535343 @default.
- W2286042919 cites W2117371402 @default.
- W2286042919 cites W2121415692 @default.
- W2286042919 cites W2123253964 @default.
- W2286042919 cites W2124149023 @default.
- W2286042919 cites W2125694416 @default.
- W2286042919 cites W2125717840 @default.
- W2286042919 cites W2127013573 @default.
- W2286042919 cites W2127106208 @default.
- W2286042919 cites W2133517541 @default.
- W2286042919 cites W2133735777 @default.
- W2286042919 cites W2138536943 @default.
- W2286042919 cites W2139715224 @default.
- W2286042919 cites W2140232641 @default.
- W2286042919 cites W2143902924 @default.
- W2286042919 cites W2144868623 @default.
- W2286042919 cites W2148049720 @default.
- W2286042919 cites W2148900871 @default.
- W2286042919 cites W2153059926 @default.
- W2286042919 cites W2156497628 @default.
- W2286042919 cites W2162098634 @default.
- W2286042919 cites W2162518284 @default.
- W2286042919 cites W2208527183 @default.
- W2286042919 cites W2313605070 @default.
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- W2286042919 doi "https://doi.org/10.1016/j.jff.2016.02.001" @default.
- W2286042919 hasPublicationYear "2016" @default.
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