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- W2286235963 abstract "Heitziquinone (7), a new benzophenanthridine alkaloid, together with five known compounds; isoarnottianamide (5), rhoifoline B (6), isobauerenol (8), 6-hydroxypellitorine (9) and sylvamide (10), were isolated as minor compounds from the hexane extract of stem bark from Zanthoxylum heitzii. Four previously reported compounds (1-4) were found, as well. Compounds 5 and 7 were both found to exist as 4:1 mixtures of two atropisomers. The structures were elucidated by 1D and 2D NMR spectroscopy and by mass spectrometry. Compounds 5-10 were identified for the first time in this species, and they are all rare natural compounds. Pellitorine (4), one of the main compounds from the hexane bark extract, was found to be responsible for the brine shrimp larvae toxicity (LC50 37 μM, 8 μg/ml) of the crude extract (LC50 24 μg/ml). Low cytotoxicity against a macrophage cell line was observed." @default.
- W2286235963 created "2016-06-24" @default.
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- W2286235963 date "2016-03-01" @default.
- W2286235963 modified "2023-10-03" @default.
- W2286235963 title "A new benzophenanthridine alkaloid and other bioactive constituents from the stem bark of Zanthoxylum heitzii" @default.
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- W2286235963 doi "https://doi.org/10.1016/j.fitote.2016.01.012" @default.
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