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- W228625344 abstract "Hypocaloric feeding decreases serum total T{sub 3} (TT{sub 3}) and production (PR) while brief cold exposure increases PR and metabolic clearance rate (MCR). The authors studied 9 men of a Navy special forces team before in Virginia and again after 2 mo extended arctic operations (EAO) in Alaska. Body weight declined in 8 of the men. This weight loss was directly correlated with a fall in skin fold thickness (r = 0.75, p < 0.008). Predicted energy intake required to maintain weight was increased + 1,886 kcal/d over predeployment conditions. There was a decrease in serum TT{sub 3} (15%), free R{sub 3} (FT{sub 3}), total thyroxine (T{sub 4}), and FT{sub 4} without a change in thyroxine binding globulin or thyrotropin. Total volume of distribution (TVd) increased by 3.76 {plus minus} 0.74 L/m{sup 2} and MCR by 13.3 {plus minus} 5.3 L/(d {center dot} m{sup 2}), while the PR showed an uncertain trend to increase by 9.84 {plus minus} 9.51 nmol/(d {center dot} m{sup 2}). Relative calorie deficits and absolute decreases in body weight with the EAO are associated with a fall in serum TT{sub 3} and FT{sub 3} that cannot be accounted for by a fall in PR. The decreasesmore » in serum T{sub 4} and T{sub 3} are, however, more closely related to an increase in MCR and TVd. The authors propose that activity and/or exposure to cold interact to modify the customary decrease in serum TT{sub 3} and PR observed with underfeeding.« less" @default.
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- W228625344 date "1991-03-11" @default.
- W228625344 modified "2023-09-22" @default.
- W228625344 title "Changes in energy intake and triiodothyronine (T sub 3 ) kinetics with extended arctic winter operations (EAO)" @default.
- W228625344 hasPublicationYear "1991" @default.
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