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• W2286832839 abstract "The present study demonstrates that the expression of c-Jun and c-Fos are elevated in gingival fibro- blast cells treated with angiotensin II and cyclosporine. The healthy human gingival tissues were collected and gingival fibroblasts were isolated and cultured. We used RT-PCR and Western blot analysis to identify the expression of c-Jun and c-Fos in cyclosporine and angiotensin II treated human gingival fibroblast cells. We found that angiotensin II in combination with cyclosporine induces c-Jun and c-Fos expressions significantly; however, the angiotensin II antagonist losartan inhibits the expression of c-Jun and c-Fos (p < 0.01). The data suggest that angiotensin II in combination with cyclosporine modulates the expression of c-Jun and c-Fos in human gingival fibroblast cells." @default.
• W2286832839 created "2016-06-24" @default.
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• W2286832839 date "2013-01-01" @default.
• W2286832839 modified "2023-09-24" @default.
• W2286832839 title "Angiotensin II stimulates expression of transcription factors c-Jun and c-Fos in cyclosporine induced human gingival fibroblasts" @default.
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• W2286832839 doi "https://doi.org/10.32604/biocell.2013.37.071" @default.
• W2286832839 hasPublicationYear "2013" @default.
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