Matches in SemOpenAlex for { <https://semopenalex.org/work/W2286957497> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W2286957497 endingPage "217" @default.
- W2286957497 startingPage "205" @default.
- W2286957497 abstract "BACKGROUND: Intracranial hypertension occurs in response to routine procedures such as endotracheal suctioning in patients with severe head injuries. In some patients, the intracranial pressure does not immediately return to baseline levels. OBJECTIVES: To examine the effect of drug administration on cerebrovascular response to endotracheal suctioning in adults with severe head injuries. METHODS: Seventy-one subjects were divided into 3 groups: those who received no drugs, those treated with opiates only (morphine sulfate and fentanyl citrate), and those treated with a neuromuscular blocking agent (vecuronium bromide) plus opiates. A controlled protocol involving 2 sequences of endotracheal suctioning that included hyperoxygenation, hyperinflation, and suctioning was used for all subjects. Two-way repeated-measures analyses of variance were done with type of drug as the between-subject factor and phase of suctioning as the within-subject factor. Survival analysis was used to compare the return of intracranial pressure to baseline levels among the 3 groups. RESULTS: Changes in intracranial pressure were significantly smaller in subjects who received a neuromuscular blocking agent plus opiates than in subjects who did not receive any drugs or received opiates only. The greatest increase in intracranial pressure from baseline was in the first and second phases of suctioning. The 3 groups showed no significant difference in the return of intracranial pressure to baseline level. CONCLUSIONS: Neuromuscular blockers attenuate the increases in intracranial pressure that occur with endotracheal suctioning. It is not known whether control of procedurally induced elevations in intracranial pressure affects long-term outcomes in adults with severe head injuries." @default.
- W2286957497 created "2016-06-24" @default.
- W2286957497 creator A5007329649 @default.
- W2286957497 creator A5022378359 @default.
- W2286957497 creator A5035999553 @default.
- W2286957497 creator A5044777277 @default.
- W2286957497 creator A5063677745 @default.
- W2286957497 creator A5067714048 @default.
- W2286957497 creator A5074912463 @default.
- W2286957497 creator A5077196542 @default.
- W2286957497 date "1998-05-01" @default.
- W2286957497 modified "2023-09-27" @default.
- W2286957497 title "Effect of neuromuscular blockers and opiates on the cerebrovascular response to endotracheal suctioning in adults with severe head injuries" @default.
- W2286957497 doi "https://doi.org/10.4037/ajcc1998.7.3.205" @default.
- W2286957497 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9579247" @default.
- W2286957497 hasPublicationYear "1998" @default.
- W2286957497 type Work @default.
- W2286957497 sameAs 2286957497 @default.
- W2286957497 citedByCount "43" @default.
- W2286957497 countsByYear W22869574972012 @default.
- W2286957497 countsByYear W22869574972013 @default.
- W2286957497 countsByYear W22869574972014 @default.
- W2286957497 countsByYear W22869574972015 @default.
- W2286957497 countsByYear W22869574972016 @default.
- W2286957497 countsByYear W22869574972017 @default.
- W2286957497 countsByYear W22869574972018 @default.
- W2286957497 countsByYear W22869574972019 @default.
- W2286957497 countsByYear W22869574972020 @default.
- W2286957497 countsByYear W22869574972022 @default.
- W2286957497 countsByYear W22869574972023 @default.
- W2286957497 crossrefType "journal-article" @default.
- W2286957497 hasAuthorship W2286957497A5007329649 @default.
- W2286957497 hasAuthorship W2286957497A5022378359 @default.
- W2286957497 hasAuthorship W2286957497A5035999553 @default.
- W2286957497 hasAuthorship W2286957497A5044777277 @default.
- W2286957497 hasAuthorship W2286957497A5063677745 @default.
- W2286957497 hasAuthorship W2286957497A5067714048 @default.
- W2286957497 hasAuthorship W2286957497A5074912463 @default.
- W2286957497 hasAuthorship W2286957497A5077196542 @default.
- W2286957497 hasConcept C2780954326 @default.
- W2286957497 hasConcept C42219234 @default.
- W2286957497 hasConcept C71924100 @default.
- W2286957497 hasConceptScore W2286957497C2780954326 @default.
- W2286957497 hasConceptScore W2286957497C42219234 @default.
- W2286957497 hasConceptScore W2286957497C71924100 @default.
- W2286957497 hasIssue "3" @default.
- W2286957497 hasLocation W22869574971 @default.
- W2286957497 hasLocation W22869574972 @default.
- W2286957497 hasOpenAccess W2286957497 @default.
- W2286957497 hasPrimaryLocation W22869574971 @default.
- W2286957497 hasRelatedWork W1553557626 @default.
- W2286957497 hasRelatedWork W1975162953 @default.
- W2286957497 hasRelatedWork W1995871151 @default.
- W2286957497 hasRelatedWork W2000421692 @default.
- W2286957497 hasRelatedWork W2010489392 @default.
- W2286957497 hasRelatedWork W2011920011 @default.
- W2286957497 hasRelatedWork W2019660199 @default.
- W2286957497 hasRelatedWork W2049538555 @default.
- W2286957497 hasRelatedWork W2140889398 @default.
- W2286957497 hasRelatedWork W2391775916 @default.
- W2286957497 hasVolume "7" @default.
- W2286957497 isParatext "false" @default.
- W2286957497 isRetracted "false" @default.
- W2286957497 magId "2286957497" @default.
- W2286957497 workType "article" @default.