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- W2287016406 abstract "1296 Objectives Radioiodine (RAI) uptake in breast tissue has been observed on RAI whole body scan in patients (pts) with differentiated thyroid cancer. Although this breast uptake has been reported in pts who has been lactating, breast uptake in pts with hyperthyroidism has not been reported or studied to our knowledge. The objective of this pilot study was to evaluate the relationship of thyroid stimulating immunoglobulin levels with breast uptake on 123I scans in pts with hyperthyroidism. Methods A prospective study was conducted on female pts who were (1) diagnosed with hyperthyroidism based upon signs, symptoms and had abnormal thyroid function tests compatible with hyperthyroidism and (2) referred for an 123I scan of the thyroid. After informed consent, anterior and lateral images of the breasts were obtained shortly after imaging of the thyroid bed. Thyroid stimulating immunoglobulin level was drawn at the time of imaging. Scans were evaluated by two reviewers (dvn/gk) for 123I uptake in the breast. Intensity was graded as 0 = background activity (bkg), 1+ = mildly >bkg, 2+ = moderately >bkg, and 3+ = >bkg. The relationship of 123I uptake in the breast was compared with the thyroid stimulating immunoglobulin levels. This was an IRB-approved study. Results Thirteen pts met the criteria above, but none of the pts had 123I breast uptake. Elevated thyroid stimulating immunoglobulin was observed in 6/13 (46%) of pts with a range of 2.42-4.6 (nl index Conclusions Based on this pilot study, increase 123I uptake in the breasts was not observed with either hyperthyroidism or elevated thyroid stimulating immunoglobulin levels" @default.
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- W2287016406 date "2011-05-01" @default.
- W2287016406 modified "2023-09-23" @default.
- W2287016406 title "The relationship of 123I breast uptake on thyroid scan to thyroid stimulating immunoglobulin in hyperthyroid patients: A pilot study" @default.
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