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• W2287102502 abstract "We hypothesized that near-infrared spectroscopy (NIRS) measures of hemoglobin and/or myoglobin O 2 saturation (IR-So 2 ) in the vascular bed of exercising muscle would parallel changes in femoral venous O 2 saturation (S[Formula: see text]) at the onset of leg-kicking exercise in humans. Six healthy subjects performed transitions from rest to 48 ± 3 (SE)-W two-legged kicking exercise while breathing 14, 21, or 70% inspired O 2 . IR-So 2 was measured over the vastus lateralis muscle continuously during all tests, and femoral venous and radial artery blood samples were drawn simultaneously during rest and during 5 min of exercise. In all gas-breathing conditions, there was a rapid decrease in both IR-So 2 and Sfv O 2 at the onset of moderate-intensity leg-kicking exercise. Although Sfv O 2 remained at low levels throughout exercise, IR-So 2 increased significantly after the first minute of exercise in both normoxia and hyperoxia. Contrary to the hypothesis, these data show that NIRS does not provide a reliable estimate of hemoglobin and/or O 2 saturation as reflected by direct femoral vein sampling." @default.
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• W2287102502 date "1999-02-01" @default.
• W2287102502 modified "2023-10-16" @default.
• W2287102502 title "Comparison of femoral blood gases and muscle near-infrared spectroscopy at exercise onset in humans" @default.
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• W2287102502 doi "https://doi.org/10.1152/jappl.1999.86.2.687" @default.
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