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- W2287207737 abstract "Only a decade ago the existence and functional significance of central nervous nicotinic acetylcholine receptors (nAChR) was still a subject of controversy. Today, the importance of this receptor class for signal transduction in human brain in normal and pathological conditions has become quite evident. nAChRs have turned out to be important pharmacological targets in disorders like Alzheimer’s disease (AD) (Arneric et al., 1994). One prerequisite to understand nAChR function is a detailed study of the cellular distribution of nAChR subtypes. In recent years several human-specific data have been made available. This paper attempts to show actual developments in this field, summarizing the expression and localization of nAChRs in human development, age and neurodegenerative states." @default.
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- W2287207737 date "1997-01-01" @default.
- W2287207737 modified "2023-10-06" @default.
- W2287207737 title "Molecular Histochemistry of Nicotinic Receptors in Human Brain" @default.
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- W2287207737 doi "https://doi.org/10.1007/978-1-4612-4116-4_39" @default.
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